“…By recapitulating the early, in utero stages of central system development, human cerebral organoids allow researchers to evaluate the neurotoxicity of a compound on a previously inaccessible window of human neurodevelopment. In a recent study, we used this approach to describe the effect of 4‐AP, a potassium channel blocker, on early neurogenesis in human cerebral organoids (Parmentier et al., 2022). Since the first description of cerebral organoids in mouse and humans, several protocols have been published both from embryonic stem cells and iPSCs (Birey et al., 2017; Eiraku et al., 2008; Giandomenico et al., 2019; Kadoshima et al., 2013; Lancaster et al., 2013; Paşca et al., 2015; Velasco et al., 2019; Yoon et al., 2019; Zafeiriou, Guobin, et al., 2020).…”