Human Heart-lung Transplantation: Physiologic Aspects of the Denervated Lung and Post-transplant Obliterative Bronchiolitis<sup>1,</sup><sup>2</sup>

Estenne, Marc; Ketelbant, P.; Primo, G; Yernault, Jean Claude

doi:10.1164/arrd.1987.135.4.976

Cited by 58 publications

(14 citation statements)

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“…Five of the patients described here have been included in previous reports. 12,13,15,17,18,20,21 Data on two patients were incomplete and were excluded from some calculations. Data are expressed as means Ϯ SD.…”

Section: Methodsmentioning

confidence: 99%

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Lung Transplantation for Lymphangioleiomyomatosis

et al. 1996

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Section: Methodsmentioning

confidence: 99%

“…In recent years, lung transplantation has become a therapeutic approach. [12][13][14][15][16][17][18] However, most lung-transplantation centers have had experience with only one or a few patients each. We therefore conducted an international survey to obtain information on transplantation for lymphangioleiomyomatosis.…”

mentioning

confidence: 99%

Lung Transplantation for Lymphangioleiomyomatosis

et al. 1996

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“…The poor response to ovarian annulment and pro gesterone therapy in cases of advanced stages of LAM, as indicated by the presence of large bullae and 'honeycomb lung' as in our case, suggests the possibil ity of pulmonary transplantation from the onset as the only viable therapeutic measure [41].…”

Section: Discussionmentioning

confidence: 57%

Lymphangioleiomyomatosis: The Effectiveness of Radiotherapy-Induced Ovarian Function Annulment

Aldeyturriaga¹,

Gómez²,

Rodríguez³

1991

Respiration

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Lymphangioleiomyomatosis is an unusual disease characterized by atypical smooth muscle hyperplasia especially of the lymphatic system and affecting females in their child-bearing years. We present a case in which ovarian function was annuled through radiotherapy, instead of resorting to the most commonly used oophorectomy, since the patient’s severe respiratory dysfunction made surgery inadviseable. The clinical, radiological and functional characteristics of this entity are discussed, and the therapeutic possibilities are reviewed

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“…In our present longitudinal study on renal transplant recipients, we have found well-preserved lung volumes in all cases studied up to 6 months after operation. The pau city of an obstructive pattern in our patients suggests that bronchiolitis obliterans, which may occur with marrow [8,9] and heart-lung [10] transplant recipients, is an uncommon complication of renal transplantation. In con trast to earlier studies which have shown diminished [4] or normal [5] DLCO, our patients have marginally raised DLCO before or shortly after transplantation (115.7 ± 9.5 and 124.5 ± 12.2% of predicted values, respectively).…”

Section: Discussionmentioning

confidence: 61%

“…Studies on pulmonary function in bone marrow trans plant recipients have demonstrasted well-preserved lung volume except in patients with graft-versus-host disease which was associated with progressive loss of FEVi [8], The underlying pathology was suspected to be bronchioli tis obliterans which has been reported in marrow [9] as well as heart-lung [10] transplant recipients. In addition, most marrow transplant recipients showed a progressive decline in DLCO [8].…”

Section: Discussionmentioning

confidence: 99%

Effect of Renal Transplantation on Pulmonary Function in Patients with End-Stage Renal Failure

Chan¹,

Lai²,

Li³

et al. 1996

Am J Nephrol

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Ten patients with end-stage renal failure on maintenance dialysis underwent serial lung function tests before and at monthly intervals after renal transplantation. Mean values of forced expiratory volume within 1 s, forced vital capacity, and total lung capacity were within the normal range before and up to 6, months after transplantation. The mean value of residual volume (RV) was above the normal range during all periods measured (157.8 ± 21.5% predicted before transplantation and 121.2 ± 17.0% predicted at 6 months after transplantation). No statistically significant changes in lung volumes were detected over a course of 6 months, but there was a trend for a reduction in RV after transplantation. The single-breath diffusion capacity for carbon monoxide (DLCO) was in the high-normal range before transplantation (115.7 ± 9.5% predicted). It remained high at 1 month after transplantation (124.5 ± 12.2% predicted), but it gradually came down to the normal range from the 2nd month onwards. At 6 months after transplantation the mean DLCO was 83.8 ± 7.3% of predicted which was significantly (p < 0.0001) lower than the value before transplantation. We conclude that raised DLCO and RV values occurred in patients with end-stage renal failure on maintenance dialysis which were most likely the result of pulmonary vascular congestion, and these abnormalities tend to improve after renal transplantation.

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Human Heart-lung Transplantation: Physiologic Aspects of the Denervated Lung and Post-transplant Obliterative Bronchiolitis^1,²

Cited by 58 publications

References 0 publications

Lung Transplantation for Lymphangioleiomyomatosis

Lung Transplantation for Lymphangioleiomyomatosis

Lymphangioleiomyomatosis: The Effectiveness of Radiotherapy-Induced Ovarian Function Annulment

Effect of Renal Transplantation on Pulmonary Function in Patients with End-Stage Renal Failure

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Human Heart-lung Transplantation: Physiologic Aspects of the Denervated Lung and Post-transplant Obliterative Bronchiolitis1,2

Cited by 58 publications

References 0 publications

Lung Transplantation for Lymphangioleiomyomatosis

Lung Transplantation for Lymphangioleiomyomatosis

Lymphangioleiomyomatosis: The Effectiveness of Radiotherapy-Induced Ovarian Function Annulment

Effect of Renal Transplantation on Pulmonary Function in Patients with End-Stage Renal Failure

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Human Heart-lung Transplantation: Physiologic Aspects of the Denervated Lung and Post-transplant Obliterative Bronchiolitis^1,²