Human Immunodeficiency Virus

Siripurapu, Rekha; Ota, Yoshiaki

doi:10.1016/j.nic.2022.07.014

Cited by 9 publications

(4 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prompt initiation of HAART is the treatment of choice and stabilization can be expected if not complete improvement. It is important to note that CNS lymphoma is a close clinical and radiological differential for space occupying opportunistic infections in patients with HIV [107] . However, in a review of primary CNS lymphoma with movement disorders presentation, none were associated with HIV [108] .…”

Section: Management Of Specific Infection-related Movement Disordersmentioning

confidence: 99%

Overview of management of infection-related movement disorders with focus on specific-infections

Holla,

Pal

2024

Clinical Parkinsonism & Related Disorders

View full text Add to dashboard Cite

Section: Management Of Specific Infection-related Movement Disordersmentioning

confidence: 99%

Overview of management of infection-related movement disorders with focus on specific-infections

Holla,

Pal

2024

Clinical Parkinsonism & Related Disorders

View full text Add to dashboard Cite

“…Recent studies have revealed that HIV infection promotes microbial translocation and immune activation by altering the microbiota [ 44 , 136 , 137 ]. These changes will accelerate opportunistic infections, such as central nervous system (CNS) opportunistic infections, including cerebral toxoplasmosis, progressive multifocal leukoencephalopathy (PML), tuberculous meningitis, cryptococcal meningitis, and cytomegalovirus infection [ 138 , 139 ]. Opportunistic infections following HIV infection might be an important factor to promote the occurrence of HIV complications.…”

Section: Intestinal Microecological Dysbiosis Promotes Hiv Complicationsmentioning

confidence: 99%

Intestinal Microbiota Dysbiosis Promotes Mucosal Barrier Damage and Immune Injury in HIV-Infected Patients

Pan,

Wu,

Jin

2023

Canadian Journal of Infectious Diseases and Medical Microbiolog

View full text Add to dashboard Cite

The intestinal microbiota is an “invisible organ” in the human body, with diverse components and complex interactions. Homeostasis of the intestinal microbiota plays a pivotal role in maintaining the normal physiological process and regulating immune homeostasis. By reviewing more than one hundred related studies concerning HIV infection and intestinal microbiota from 2011 to 2023, we found that human immunodeficiency virus (HIV) infection can induce intestinal microbiota dysbiosis, which not only worsens clinical symptoms but also promotes the occurrence of post-sequelae symptoms and comorbidities. In the early stage of HIV infection, the intestinal mucosal barrier is damaged and a persistent inflammatory response is induced. Mucosal barrier damage and immune injury play a pivotal role in promoting the post-sequelae symptoms caused by HIV infection. This review summarizes the relationship between dysbiosis of the intestinal microbiota and mucosal barrier damage during HIV infection and discusses the potential mechanisms of intestinal barrier damage induced by intestinal microbiota dysbiosis and inflammation. Exploring these molecular mechanisms might provide new ideas to improve the efficacy of HIV treatment and reduce the incidence of post-sequelae symptoms.

show abstract

“…1 It is the primary cause of HIV infection, leading to Acquired Immunodeficiency Syndrome (AIDS), a condition that has posed a formidable challenge to the medical and scientific communities since its emergence in the late 20th century. 2 HIV-1 is characterized by its ability to attack the body's immune system, specifically targeting CD4+ T cells, which play a crucial role in orchestrating the body's immune response. 3 As the virus replicates and depletes these cells, it progressively weakens the immune system, leaving the body vulnerable to a range of opportunistic infections and diseases that define the late stage of the infection, known as AIDS.…”

Section: Introductionmentioning

confidence: 99%

Quantum enhancement in the limit of detection measurement of a phase-based plasmonic biosensor including loss

Mpofu,

Mthunzi-Kufa

2024

Quantum Effects and Measurement Techniques in Biology and Biophotonics

View full text Add to dashboard Cite

Quantum states of light allow for highly sensitive biosensing configurations, surpassing the limitations imposed by shot-noise. In this theoretical study, we focus on optical plasmonic sensors, which have extensive applications in disease diagnostics, including detection of diseases like HIV. Our investigation involves simulating the impact of quantum states of light, such as the NOON state and squeezed states, on enhancing the limit of detection in a plasmonic phase-sensing biosensor, surpassing coherent light states' shot-noise limit. Specifically, we explore the use of quantum states to improve the limit of detection in phase-based biosensors for HIV detection, operating below the shot-noise limit. Through our analysis, we demonstrate that incorporating quantum states of light in surface plasmon resonance (SPR) biosensing leads to enhanced performance compared to classical states. Moreover, we take into account the impact of environmental losses in the biosensing setup, considering the realworld challenges in practical implementation. Our findings emphasize the potential of quantum SPR biosensors in the development of novel disease diagnostics devices.

show abstract

Human Immunodeficiency Virus

Cited by 9 publications

References 62 publications

Overview of management of infection-related movement disorders with focus on specific-infections

Overview of management of infection-related movement disorders with focus on specific-infections

Intestinal Microbiota Dysbiosis Promotes Mucosal Barrier Damage and Immune Injury in HIV-Infected Patients

Quantum enhancement in the limit of detection measurement of a phase-based plasmonic biosensor including loss

Contact Info

Product

Resources

About