Moral transhumanism is a project that aims to enhance human beings by using modern technology in a morally beneficial way. This article discusses the problems and ethical dilemmas raised by transhumanism, notably whether (moral) virtues may be enhanced in the proposed manner. To achieve this end, moral transhumanism primarily proposes the use of genetic technology and pharmacology. Regarding moral virtues, the article suggests that sensitivity to reasons is a fundamental feature of human moral cognition. Enhancing moral virtues would diminish this sensitivity or assign it a superfluous role while jeopardizing the person’s autonomy and self-determination.