8. The traditional classification of hypoxia has only two subgroups based on empirical observations i.e., chronic and acute hypoxia (Fig. 3). Acute hypoxia response occurs within minutes of exposure to a hypoxic environment i.e., symptoms occur in first few hours-days. Some of the symptoms are hyperventilation, insomnia, fatigue, dizziness and gastrointestinal disturbances. In chronic hypoxia, the term 'chronic' is used to indicate the time interval which ranges over weeks and months. However long term adaptation to hypoxia has been studied in human populations in Himalayas, Ethiopian and Andes over generation 9 . According to Best and Taylor 10 hypoxia is classified into four main type's i.e., Hypoxic hypoxia, anemic hypoxia, stagnant hypoxia and histotoxic hypoxia as shown in Fig. 4.
Nutritional Requirement at High-altitude with Special Emphasis to
ABSTRACTWhen people are exposed to the extreme environmental conditions, such as high altitude where there is decrease in temperature and partial pressure of oxygen induces fatigue, insomnia, loss of appetite and increased cardiac output. Hence there is need to improve the appetite through the diet and digestion clout of the individual. In the present review paper the efficiency of digestion is compromised at high altitude is discussed. Also about, Hypoxia, resulting by decreased partial pressure of oxygen can be classified into acute hypoxia and chronic hypoxia based on the exposure time. There is increased formation of reactive oxygen species due to less oxygen available in the air at high altitude which leads to oxidative stress. Lipid peroxidation caused by oxidative stress. Hypoxia is mediated through hypoxia inducible factors which maintain oxygen haemostasis in the body. At high altitude diet rich in carbohydrates have been found to be beneficial as it increases glucose metabolism. Requirement of nutrients such as vitamin A, vitamin E and vitamin C as well as micronutrients such as zinc, iron, selenium, copper and manganese will be required at high altitude. Hypoxia effect on the intestine leads to malabsorption and the lipid storage is stimulated and lipid catabolism is inhibited through β-oxidation. Defence Life Science Journal, Vol. 2, No. 2, April 2017, pp. 120-127, DOI : 10. Hypoxic hypoxia is caused when there is low oxygen tension in the inhaled air as a result of which the haemoglobin present in the erythrocyte cannot saturate the fully saturate with oxygen leading to lack of oxygen in arterial blood. This is one of the most serious forms of hypoxia. Anemic hypoxia is a less serious condition than hypoxic hypoxia and it may be caused by an insufficient transport function of the haemoglobin. Stagnant/ Circulatory hypoxia arises when the amount of oxygen reaching the tissue is inadequate. This turn leads to reduced rate of blood circulation thereby allowing accumulation of carbon dioxide in the tissue. Histotoxic hypoxia is a condition where there is normal amount of oxygen in the blood and under normal tension but the cells are unable to accept oxygen...