Human papilloma virus (HPV) vaccination: Questions and answers

Mejilla, Allison; Li, Emily; Sadowski, Cheryl A

doi:10.1177/1715163517712534

Cited by 10 publications

(10 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In general, treatment options include topical cream appliance with several substances, cryotherapy, laser therapy or surgical removal of any visible lesion [5]. HPV vaccination programs running the last decade for school-aged girls and boys have managed to reduce anogenital warts by 62%, cervical cancer by 45% and anal cancer by 54% [6]. In certain rare cases, warts may gain giant sizes (Buschke - Loewenstein tumor) and create a treatment challenge.…”

Section: Discussionmentioning

confidence: 99%

Extensive anogenital warts: a multidisciplinary surgical management

Chondros¹,

Graikos²,

Klambatsas³

et al. 2018

Pan Afr Med J

View full text Add to dashboard Cite

Genital warts are a major worldwide healthcare problem of sexually active population. Apart from direct association with cervical cancer, male patients experience HPV-related condylomata in several locations in the anogenital area. Extensive growth, multifocality and difficult accessibility wart sites are demanding and often require multidisciplinary surgical management. In our case, we present a male patient with extensive anogenital warts treated by a team of surgeons in several steps.

show abstract

Section: Discussionmentioning

confidence: 99%

Extensive anogenital warts: a multidisciplinary surgical management

Chondros¹,

Graikos²,

Klambatsas³

et al. 2018

Pan Afr Med J

View full text Add to dashboard Cite

show abstract

“…Cervarix is based on the HPV 16 and HPV 18 antigens and proprietary adjuvants for enhancement of immunogenicity [65]. While Gardasil provides protection against wide range of HPV such as HPV 6, HPV 11, HPV 18, HPV 31, HPV 33, HPV 45, HPV 52, and HPV 52 [66]. All the vaccines are intended to provide complete protection against HPV if administered before the exposure and have been shown to be highly efficacious without any adverse effects.…”

Section: Prevention and Treatmentmentioning

confidence: 99%

Recent Advances in Human Papillomavirus Infection and Management

Saxena¹,

Kumar²,

Goel³

et al. 2019

Current Perspectives in Human Papillomavirus

View full text Add to dashboard Cite

Human papillomavirus (HPV) accounts for approximately 4.5% of all cancers which differs at the level of economic development and geographical regions. The life cycle of the HPV is completely dependent on the epithelium differentiation without the involvement of cell death and systemic viremia. Carcinogenesis is the consequence of viral gene expression, dysregulated cell proliferation, and genomic instability. Keratinocytes are the target cell for HPV which act as the physical and immunological barrier. In cervical carcinogenesis, the enhanced level of Th17 infiltration has been observed which increases with the disease progression and is coupled with CCL20 expression in the stromal mesenchymal compartment. IL-6 and M-CSF are known as "switch factors" which are imperative for pro-tumorigenic response in monocytes. Screening of cervical cancer includes three major procedures: cytology, nucleic acid test, and co-testing. For evaluating anal lesions, high-resolution anoscopy is performed which is similar to colposcopy. Prophylactic vaccination is the primary preventive measure to control the HrHPV infection and reduce the burden of HPV-related cancer. The precancerous stage of HPV infection includes excision, ablation, and immunotherapy. Radiotherapy is the acceptable primary treatment for the early stage of anogenital cancer, whereas for the advanced-stage metastatic cancer, palliative therapy is the only option.

show abstract

“…In all Canadian jurisdictions, such school-based programs currently offer HPV vaccination for both girls and boys (targeting 1 or more cohorts across grades 4-7, plus catch-up groups). [18][19][20] Coverage rates for public HPV vaccination programs vary across jurisdictions, with uptake ranging from 40% (Manitoba) to 90% (Newfoundland), as of June 2013. 19 Since its introduction in Canada, the HPV vaccine has had significant impact in adolescents.…”

Section: Available Vaccinesmentioning

confidence: 99%

“…[18][19][20] Coverage rates for public HPV vaccination programs vary across jurisdictions, with uptake ranging from 40% (Manitoba) to 90% (Newfoundland), as of June 2013. 19 Since its introduction in Canada, the HPV vaccine has had significant impact in adolescents. In studies looking at HPV-related conditions preand postvaccine, there has been an 86% decline in the incidence risk ratio of precancerous cervical cells among females aged 15 to 17 years (British Columbia) and a 45% decline in genital warts incidence rates among females aged 15 to 19 years (Quebec).…”

Section: Available Vaccinesmentioning

confidence: 99%

“…Pharmacists have a responsibility to provide accurate information and address potential misconceptions (e.g., regarding pneumococcal vaccine recommendations and funding, HZ vaccine efficacy and/or HPV vaccination and sexual activity). 19 This will ensure patients can make informed decisions regarding vaccination and help overcome potential barriers to vaccine uptake. In summary, pharmacists must advocate for vaccination to minimize infection and improve public health outcomes, taking patient values into account.…”

Section: Start the Conversationmentioning

confidence: 99%

See 1 more Smart Citation

The role of pharmacists in providing recommended vaccines

Oleksyn¹

2019

Can Pharm J

View full text Add to dashboard Cite

In Canada, the National Advisory Committee on Immunization (NACI) makes recommendations for vaccination. 1,2 However, vaccines that are publicly funded vary by province and territory, largely based on cost effectiveness and budget capacity, rather than clinical indication and vaccine effectiveness. Using their full scope of practice, pharmacists have a unique opportunity to offer recommended protection against vaccine-preventable diseases to patients. Pneumococcal vaccines Disease burden Streptococcus pneumoniae is a bacterium that causes invasive pneumococcal disease (IPD), such as bacteremia and meningitis, and is a common cause of community-acquired pneumonia (CAP). There are over 90 serotypes recognized worldwide, 15 of which cause the majority of disease. S. pneumoniae can spread from person to person by droplets from the nose or mouth, by sneezing or coughing. 3

show abstract

Human papilloma virus (HPV) vaccination: Questions and answers

Abstract: 3 0 6 C P J / R P C • S e p t e m b e r / O c t O b e r 2 0 1 7 • V O L 1 5 0 , N O 5 clinical review PeeR-ReViewed

Cited by 10 publications

References 19 publications

Extensive anogenital warts: a multidisciplinary surgical management

Extensive anogenital warts: a multidisciplinary surgical management

Recent Advances in Human Papillomavirus Infection and Management

The role of pharmacists in providing recommended vaccines

Contact Info

Product

Resources

About