Human Papilloma Virus Vaccine in Indian Settings: Need of the Hour

Rathi, Akanksha; Garg, Suneela; Meena, GS

doi:10.4172/2157-7560.1000346

Cited by 3 publications

(6 citation statements)

References 17 publications

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“…This protection is higher in individuals who are negative for hrHPV and HPV. 16,18 Vaccination in women between 25-45 years, the effect on pre cancer is smaller, as they would be already exposed to HPV and vaccination wouldn't clear the infection. 19 With the present study we found that the overall awareness of HPV infection was better among medical students and most important source of information was medical college teaching.…”

Section: Discussionmentioning

confidence: 99%

“…15 Natural infections with HPV induces a weak immune response which may not be protective whereas vaccination results in a strong immune response. 16 Although the impact of vaccination on cancer cervix is awaited, countries which have introduced HPV immunization program have reported reduction in prevalence of vaccine type HPV infections. 9 Herd immunity and cross-protection are known to augment the impact of vaccine.…”

mentioning

confidence: 99%

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Human papilloma virus vaccination: knowledge, awareness and acceptability among medical and paramedical students

Hoblidar

Moni

Desai

et al. 2020

Int J Reprod Contracept Obstet Gynecol

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Background: Cervical cancer is the second leading cause of death in india. it is also one of the few malignancies where an infectious etiological agent human papilloma virus (HPV) has been identified. With the advent of HPV vaccination, it is possible to reduce the morbidity and mortality associated with carcinoma cervix. But biggest hurdle to achieve this is the lack of awareness about the availability and use of HPV vaccine. This study was conducted to know knowledge and awareness of HPV infection and vaccination among medical and paramedical students. We also evaluated the acceptability and coverage of HPV vaccine among these students.Methods: This study was conducted among a total of 520 female students of the Sri Dharmasthala Manjunatheshwara University with the help of a questionnaire. The study group included 207 MBBS students, 167 BDS students, 89 nursing students and 57 physiotherapy students.Results: Most of the students were in 18-20 years’ age group. Nearly 40.57% of the students knew that HPV is sexually transmitted and 29.80% were aware that this infection can be prevented. Availability of HPV vaccine was known to 75% of the students and the main source of their information was through their college teachings. Nearly 43.75% of the students knew HPV vaccine protects against cervical cancer and 26.73% of the students were vaccinated. Overall knowledge and awareness were better among medical students.Conclusions: A lot of work needs to be done so as to make the target population accept HPV vaccine. There is a great difference between awareness of availability of the vaccine and its use. This emphasizes the need for health care professionals to take special interest in promoting this vaccine in the general population.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Human papilloma virus vaccination: knowledge, awareness and acceptability among medical and paramedical students

Hoblidar

Moni

Desai

et al. 2020

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

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“…Cervical cancer is the fifth most common cancer in the world and third most common cancer in India, which accounts for 26.5% of global cervical cancer cases. 7 Cervical cancer is the second leading cause of cancer-related deaths in women aged 15–44 years. 8 It is estimated that the incidence of cervical cancer is 122,844 with a death rate of 67,477 per year.…”

Section: Introductionmentioning

confidence: 99%

“… 8 It is estimated that the incidence of cervical cancer is 122,844 with a death rate of 67,477 per year. 7 The major risk factor for cervical cancer is human papilloma virus (HPV) infection. Cervical cancer is ranked as the most frequent cancer in women in India, and they face a 2.5% cumulative lifetime risk and 1.4% cumulative death risk from cervical cancer.…”

Section: Introductionmentioning

confidence: 99%

“…The most common strains which are associated with cervical cancer are HPV-16 and 18 and account for more than 75% of cervical cancer cases in India. 7 , 8 The use of HPV vaccine has proved to reduce the incidence rate of cervical cancer by over 50%. 9 There are two HPV vaccines commercially available in India (Gardasil, a quadrivalent vaccine and Cervarix- a bivalent vaccine) since 2008 and are recommended for adolescent girls aged 9–14 years; however, vaccination can be extended up to the age of 26 years.…”

Section: Introductionmentioning

confidence: 99%

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Impact of indirect education on knowledge and perception on cervical cancer and its prevention among the parents of adolescent girls: an interventional school-based study

Jacob

Abraham

Thomas

et al. 2021

Therapeutic Advances in Vaccines and Immunotherapy

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Background: India has almost 225 million adolescent girls and they seem to be at a disadvantage, both economically and by their lack of knowledge on human papilloma virus (HPV) vaccine, when compared to adolescent girls of other Asian countries. Aim: To assess the prevalence of HPV vaccination and to identify the impact of education in improving the knowledge and perception about the HPV infection and vaccination among the parents of adolescent girls. Methodology: The prospective interventional study was conducted in four schools within a South Indian City, Mysuru. The informed consent form and the questionnaire were sent home with the identified adolescent girls during the pre-interventional phase. Educational sessions were conducted for the students in their school and an education leaflet was distributed to their parents. Three weeks later, questionnaires were re-administered to the parents via the enrolled girls and their responses were collected. Results: The prevalence of HPV vaccination in the study population was 4.4%. There was a statistically significant improvement in knowledge in the post-interventional phase of the study ( p = 0.001), but could not identify a significant change in their perception ( p = 0.479). Parents belonging to the socioeconomic class of upper middle and upper lower showed better improvement at the end of the study, with a percentage improvement of 58.93% and 48.44%, respectively. Conclusion: The study proved that the healt care professional can target school children to communicate effectively to their parents on the importance of HPV vaccine as the study clearly observed a positive behavioral change among the study population.

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Prevalence and distribution of HPV 16 and 18 with its epidemiological profile among cervical cancer patients: A prospective study from regional cancer centre of Gujarat, Western India

Parekh,

Patel,

Dave

et al. 2024

IJOGR

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Cervical cancer (CC) is the leading cause of morbidity and mortality due to cancer among women in Indian. This study was conducted to determine the prevalence and distribution of HPV16/ 18 and epidemiological profile of CC patients from, Gujarat Western India.CC biopsy specimens of 400 patients were analyzed for HPV16 and 18 by type-specific PCR. In our study 74% of CC cases were positive for HPV, 67% had HPV16, 14.8% had HPV18 and 7.7% had both HPV16/18. The median age of the women with CC was 50 years and peak incidence (31.8%) was between 40 to 50 years. Majorities (68.5%) were postmenopausal. The median age of marriage was 20years. Squamos cell carcinoma (SCC) was found in 91% and adenocarcinoma (ADC) in 7.3% of the patients. As per study 7.8%, 16.3%, 58% and 2.5% of CC patients presented in FIGO stage I, II, III, and IV respectively. HPV16 was exhibited in, 68.8% and 66.4%, HPV18 in 14.9% and 15.9% of pre and postmenopausal patients respectively. HPV16 and HPV 18 positivity was 68.7% and 51.7% and 13.2% and 31% in SCC and in ADC respectively. HPV16 infection was higher in stage I and HPV18 in stage IV malignancy.There were two peaks of HPV16, first between 21 to 30 and second between 51 to 60 years among CC patients. HPV 16 is highly prevalent among all groups. In patients with adenocarcinoma, Stage IV malignancy & who had marriage before 18years, incidence of HPV18 was relatively high.

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Human Papilloma Virus Vaccine in Indian Settings: Need of the Hour

Cited by 3 publications

References 17 publications

Human papilloma virus vaccination: knowledge, awareness and acceptability among medical and paramedical students

Human papilloma virus vaccination: knowledge, awareness and acceptability among medical and paramedical students

Impact of indirect education on knowledge and perception on cervical cancer and its prevention among the parents of adolescent girls: an interventional school-based study

Prevalence and distribution of HPV 16 and 18 with its epidemiological profile among cervical cancer patients: A prospective study from regional cancer centre of Gujarat, Western India

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