Human Papillomavirus (HPV) Infection in Women Participating in Cervical Cancer Screening from 2006 to 2010 in Shenzhen City, South China

Abstract

The prevalence of HPV 18 infection is increasing faster than any others, which will lead it to be one of the main subtypes in this city in the future.

Genotype Distribution of Human Papillomavirus in Women with Abnormal Cervical Cytology in an Esophageal Carcinoma High Incidence Area of China

“…The strength of this study was that the age for participants covered from 18-81 years. Generally, the vast majority of the HPV prevalence was 19.76% in total participants and was higher than 13.8% of a hospital-based study in Shenzhen near to Shantou (Wang et al, 2013). For age-specific distribution, a higher prevalence of HPV infection was observed in both young (18-25 years) and old (> 65 years) age groups in the general population, in agreement with the previous report in Hunan population, mid-south China .…”

Prevalence and Genotype Distribution of Human Papillomavirus among Women from Henan, China

“…A high rate of HPV-DNA infection (44.4%) was observed in specimens taken from patients ranged from 17 to 79 years, and 35.1% was the HR-HPV types. The prevalence of HPV infection among females attending the cervical cancer screening varies in different regions of China, for example, in Shenzhen city, 13.8% of the volunteers was HPV positive; in Shanghai city, southeast of China, the infection rate was 30.2% (Xue et al, 2009;Wang et al, 2013). In the present study, the prevalence of HPV infection showed a significant difference among patients in the age groups (χ 2 =22.279, p<0.05).…”

“…Our findings showed the most prevalent HPV genotype was HPV 16 (9.2%, 53/578), followed by HPV 52 (7.8%, 45/578), HPV 6 (6.9%, 40/578), HPV 11 (5.9%, 34/578), HPV 42 (5.0%, 29/578) and HPV 58 (3.8%, 22/578), which was similar to that of Beijing city (Hou et al, 2012). In other regions of China, for example, in Zhejiang province, a coastal region in southeast China, the most predominant type was HPV 52 (3.1%), followed by HPV 16 (2.5%), HPV 58 (2.1%), HPV 68 (1.0%) and HPV 81 (0.9%) (Ye et al, 2010); in Shenzhen city, the five most commonly found HPV types were HPV 16 (3.47%), HPV 58 (1.68%), HPV 33 (1.38%), HPV 43 (1.36%) and HPV 18 (1.27%) (Wang et al, 2013). The difference may be due to the geographical and biological interplay between HPV types or variants and host immunogenic factors (Xue et al, 2009).…”

“…It was reported that the persistence rate of the HR-HPV infection was higher than LR-HPV infection, and it was a strong predictor for the development of CIN2/3 and invasive cervical cancer (Dalstein et al, 2003;Datta et al, 2012). The previous work found that the HR-HPV DNA was positive among 80% of patients with cervical cancer, so more inspections, including cytology and even colposcopy, should be proceed among women aged >60 years for the prevention of cervical cancer (Wang et al, 2013). Our findings showed the most prevalent HPV genotype was HPV 16 (9.2%, 53/578), followed by HPV 52 (7.8%, 45/578), HPV 6 (6.9%, 40/578), HPV 11 (5.9%, 34/578), HPV 42 (5.0%, 29/578) and HPV 58 (3.8%, 22/578), which was similar to that of Beijing city (Hou et al, 2012).…”

“…It is reported that the distribution and prevalence of HPV varied by geographic regions, even in different areas of the same country (Wheeler et al, 2009). Although a series of studies have been conducted to assess the prevalence of HPV genotypes in China, such as Shanghai, Zhejiang and, Shenzhen, fewer are referred to Henan province (Xue et al, 2009;Ye et al, 2010;Wang et al, 2013).…”