Human papillomavirus infection and ultraviolet light exposure as epidermoid inclusion cyst risk factors in a patient with epidermodysplasia verruciformis?

Ramagosa, Ryan; Villiers, Ethel Michele De; Fitzpatrick, James E.; Dellavalle, Robert P.

doi:10.1016/j.jaad.2007.01.032

Cited by 20 publications

(19 citation statements)

References 30 publications

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“…3 Verrucous cysts located elsewhere on the body typically are not connected to the epidermal surface and have been associated with HPV types 20, 34, 8, and 6. 4,5 The presence of the HPV virus has traditionally been demonstrated with molecular methods and IHC staining for HPV antigens 1,2,6 ; however, our case represents the first reported instance, to our knowledge, demonstrating the presence of HPV with p16 positivity in a verrucous cyst.…”

Section: Report Of a Casementioning

confidence: 67%

Verrucous Cyst With Melanocytic and Sebaceous Differentiation: A Case Report and Review of the Literature

Hardin

Gardner

Colomé

et al. 2013

Archives of Pathology &Amp; Laboratory Medicine

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A 58-year-old woman presented with a cystic skin lesion. Microscopic examination showed an intradermal cyst lined by acanthotic squamous epithelium with squamous eddies and compact hyperkeratosis, and changes typical of verrucous lesions. Mature sebaceous cells and dendritic melanocytes were present as well. To our knowledge, this is the first report of a verrucous cyst with areas of sebaceous differentiation and melanocytes. Verrucous cysts are well-known, benign lesions with a clear histologic pattern. Histologically, they resemble verruca vulgaris with acanthosis, hypergranulosis, dense keratohyaline granules, and viral cytopathic effects seen. Until now, melanocytes and mature sebaceous cells in the cyst lining have not been reported. We do not feel that these findings alter the expected benign nature of this lesion. Instead, we report this case to suggest the possible adnexal embryonic origin, given the presence of sebaceous cells and dendritic melanocytes that support this histologic lineage in our specific case.

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Section: Report Of a Casementioning

confidence: 67%

Verrucous Cyst With Melanocytic and Sebaceous Differentiation: A Case Report and Review of the Literature

Hardin

Gardner

Colomé

et al. 2013

Archives of Pathology &Amp; Laboratory Medicine

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“…The cysts in Ramagosa et al . 's study arose in the chest, a sun exposed area, of a patient with EV, and EV‐HPV have been detected in plucked hairs from various body sites . Ramagosa et al .…”

Section: Discussionmentioning

confidence: 99%

“…'s study arose in the chest, a sun exposed area, of a patient with EV, and EV‐HPV have been detected in plucked hairs from various body sites . Ramagosa et al . therefore deduced that ultraviolet light may induce local immunosuppression to facilitate the activation of latent HPV infection of the follicular epithelium and thus lead to cystic growth of the epithelium.…”

Section: Discussionmentioning

confidence: 99%

Human papillomavirus type 6/11 identified in an epidermoid cyst of the scrotum

Kawase

Egawa

Ishiji

et al. 2017

The Journal of Dermatology

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To date, epidermoid cysts associated with human papillomavirus (HPV) infection have been described mainly in palmoplantar locations, and have involved HPV types 60 and 57. In contrast, HPV-6/11 is a major cause of condyloma acuminatum. Here, we report the case of a healthy 31-year-old man who presented to our clinic with a 1-month history of a 1-cm, reddish-brown, cystic scrotal tumor with a punctum. The lesion was studied histologically, immunohistochemically and by DNA-DNAin situ hybridization. Histology revealed an epidermoid cyst with vacuolated keratinocytes with shrunken nuclei (koilocytes) in the cyst wall. Immunostaining was positive for HPV antigens and in situ hybridization revealed HPV-6/11 DNA in the koilocytes. This is the first report of an HPV-6/11-associated epidermoid cyst in the anogenital skin of an immunocompetent individual.

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“…Ultraviyole ışığa maruz kalma, doku travması (cerrahi dâhil), sigara ve human papilloma virüsü ile ilişkili bulunmuştur. Epidermoid kistler gardner sendromunun bir parçası olarakta gö-rülmektedir (5)(6)(7)(8)(9) .…”

Section: Discussionunclassified

Benign Epidermal Perianal Inclusion Cysts

Bayar¹,

Bademci²,

Subasi³

2016

Okmeydani Medical Journal

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Human papillomavirus infection and ultraviolet light exposure as epidermoid inclusion cyst risk factors in a patient with epidermodysplasia verruciformis?

Abstract: Background-Epidermoid inclusion cysts are common lesions with unclear etiology.

Cited by 20 publications

References 30 publications

Verrucous Cyst With Melanocytic and Sebaceous Differentiation: A Case Report and Review of the Literature

Verrucous Cyst With Melanocytic and Sebaceous Differentiation: A Case Report and Review of the Literature

Human papillomavirus type 6/11 identified in an epidermoid cyst of the scrotum

Benign Epidermal Perianal Inclusion Cysts

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