Human Papillomavirus Infection in Men Who Have Sex With Men Participating in a Dutch Gay-Cohort Study

Abstract

In this study, anal HPV DNA was detected more often than HPV DNA at the coronal sulcus. HIV positivity was associated with a higher prevalence of high-risk, but not with low-risk HPV types, at the anus. No association was found between HIV positivity and presence of high-risk HPV at the coronal sulcus. No sexual behavioral determinants for the presence of HPV could be identified. Concomitant anal infection with C trachomatis, gonococci, or herpes simplex virus may be associated with HPV infection. In the majority of steady couples, partners were infected with different HPV types.

Human Papillomavirus Prevalence and Type Distribution in Male Anogenital Sites and Semen

“…8,9,[11][12][13][14][15][16][17][18][19][20]. Consistently, the prepuce has the highest proportion of HPV-positive samples.…”

“…Table 3. Prevalence of type-specific HPV infection by anatomic site or specimen, HPV Detection in Men study (N = 463) Infection at any site (n = 463) Penile shaft (n = 449) Glans/corona (n = 444) Scrotum (n = 441) Perianal area (n = 436) Anal canal (n = 386) Urethra (n = 278) Semen (n = 337) 8,11,[17][18][19]. However, lack of comparability of sampling sites included in these studies and in others wherein samples were pooled from different anatomic sites makes direct comparison difficult.…”

High Prevalence of Human Papillomavirus Infections in Urine Samples from Human Immunodeficiency Virus-Infected Men

“…Apparently, HIV alters the natural history of HPV infection through an HIV-impaired immune system, resulting in an increased risk for the development of cervical cancer (9). Although many data are available from HPV studies in women (7,12,14,21), data on infections in men are very limited (30). In most cases HPV infection in men is subclinical, resulting in a reservoir of asymptomatic carriers who can serve as vectors for the virus.…”

Human Papillomavirus Infection in Men Who Have Sex with Men in Lima, Peru

“…3 The prevalence of anal HPV in HIV-positive MSM is often double that in HIV-negative men. 4,5 As CD4 cell counts decrease, the prevalence of HPV infection, the number of HPV types per individual, and the rate of cellular dysplasia increase. 6 The risk of invasive and in situ anal carcinoma in HIV-positive MSM is 37.9 and 60.1 times greater than men in the general population, respectively.…”