2017
DOI: 10.1111/his.13162
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Human papillomavirus‐related carcinoma with adenoid cystic‐like features of the sinonasal tract: clinical and morphological characterization of six new cases

Abstract: We report six new cases of HPV-related ACC-like carcinoma and found that, although in a small material, the prognosis for these patients seems more favourable than for ACC. For the distinction between ACC and HPV-related ACC-like carcinoma, p16, MYB immunohistochemistry or investigation of MYB, MYBL1 and NFIB gene status are valuable.

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Cited by 48 publications
(60 citation statements)
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“…Fourteen of the cases had been previously published. (8, 10) Study approval was obtained from the Johns Hopkins University Internal Review Board (IRB00096402). The cases were all reviewed centrally (JAB) and various histologic features were characterized.…”
Section: Methodsmentioning
confidence: 99%
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“…Fourteen of the cases had been previously published. (8, 10) Study approval was obtained from the Johns Hopkins University Internal Review Board (IRB00096402). The cases were all reviewed centrally (JAB) and various histologic features were characterized.…”
Section: Methodsmentioning
confidence: 99%
“…(8, 10) DNA was extracted from five micron-thick slides containing formalin-fixed paraffin-embedded tumor samples. Briefly, tissues were deparaffinized using xylene, macrodissected from the slides, and underwent digestion with 50 μg/mL proteinase K (Boehringer Mannheim) in the presence of 1% sodium dodecylsuflate at 48°C for 2 days.…”
Section: Methodsmentioning
confidence: 99%
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