Human Papillomaviruses in Anogenital Epithelial Lesions

Kato, Madoka; Shimizu, Akira; Takeuchi, Yûkô; Hattori, Tomoyasu; Abe, Masatoshi; Amano, Hodaka; Motegi, Sei‐ichiro; Tamura, Atsushi; Ishikawa, Osamu

doi:10.2340/00015555-1784

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…Recently, HPV infection has attracted attention due to its etiological role in the development of penile carcinomas including genital BD. 2,6,[10][11][12] In particular, anogenital BD is likely to be involved with HPV infection, and HPV16 is often detected in genital BD tissues. 11 However, limited studies have investigated the etiological role of HPV in the development of genital HPV-positive BD.…”

Section: Discussionmentioning

confidence: 99%

Human papillomavirus 16–positive penile Bowen’s disease involving the distal urethra: A case report

Sakamoto

Shigehara

Shimizu

et al. 2020

SAGE Open Medical Case Reports

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A 79-year-old man visited our hospital with a chief complaint of erythema around the urethral orifice of the glans, and a diagnosis of penile Bowen’s disease was made by penile skin biopsy. Initially, local tumor resection with skin grafting from the femoral skin was performed. However, histopathological examination revealed a positive urethral margin of tumor. Since the degree of urethral lesion of penile Bowen’s disease was unclear, the patient received glansectomy. Histopathological examination revealed a tumor lesion in the distal urethra, 7 mm from the external urethral orifice, and confirmed the complete resection of urethral Bowen’s disease. The patient recovered well, with no definite recurrence of Bowen’s disease up to 13 months after partial penectomy. Human papillomavirus 16 DNA was detected in the paraffin-embedded tumor sample, and in situ hybridization confirmed human papillomavirus 16 DNA locations in the tumor tissue. Immunohistochemistry revealed that p16-INK4a was widely expressed in the tumor tissue.

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Section: Discussionmentioning

confidence: 99%

Human papillomavirus 16–positive penile Bowen’s disease involving the distal urethra: A case report

Sakamoto

Shigehara

Shimizu

et al. 2020

SAGE Open Medical Case Reports

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“…Although a few cases of bowenoid papulosis have been reported to be associated with HPV type 67 (6), to the best of our knowledge, this is the first case of nail BD associated with HPV type 67 (7,8). HPV type 67 was initially cloned from a lesion of vaginal intraepithelial neoplasia (9).…”

Section: Detection Of Human Papillomavirus Type 67 In Subungual Bowenmentioning

confidence: 99%

Detection of Human Papillomavirus Type 67 in Subungual Bowen’s Disease Presenting as Longitudinal Melanonychia

Shimizu¹,

Yasuda²,

Hoshijima³

et al. 2015

Acta Derm Venerol

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Human Papillomaviruses in Anogenital Epithelial Lesions

Cited by 2 publications

References 6 publications

Human papillomavirus 16–positive penile Bowen’s disease involving the distal urethra: A case report

Human papillomavirus 16–positive penile Bowen’s disease involving the distal urethra: A case report

Detection of Human Papillomavirus Type 67 in Subungual Bowen’s Disease Presenting as Longitudinal Melanonychia

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