The use of robots in the national economy-especially in industrialized countries-is growing. At the same time, the interdependency between humans and robots is getting increasingly closer: they are engaging in direct contact with each other as more and more organizations let robots and humans work hand-in-hand. One factor that predicts successful human-robot interdependency is the acceptance of the robot by the human. Generally, only when an innovative assistive working system covers human needs and expectations, it is perceived to be useful and hence accepted. Furthermore, it has been found that cultural context has an impact on human-robot interaction, as people feel more comfortable interacting with a robot in a culturally normative way. Therefore this paper aims at presenting a human-robot collaboration acceptance model (HRCAM) with regard to the collaboration between humans and robots that is based on prior acceptance models, while also considering technology affinity and ethical, legal and social implications. Additionally, similarities and differences in robot acceptance are shown for four selected countries-both in comparison to the overall human-robot collaboration acceptance model and between the countries. The HRCAM additionally shows which variables influence perceived usefulness and perceived ease of use, and thus behavioral intention to use and use behavior. A further distinction is made between anchor variables, which can be influenced in the long term, and adjustment variables, which can be influenced in the short to medium term. The model therefore offers practitioners in the field of human-robot collaboration recommendations to increase the acceptance of robots. Keywords Technology acceptance • Human-robot interaction • Human-robot cooperation • Human-machine interaction • Cross-cultural differences • TAM