Human sensory nerve compound action potential amplitude: variation with sex and finger circumference.

Bolton, C F; Carter, K M

doi:10.1136/jnnp.43.10.925

Cited by 103 publications

(67 citation statements)

References 6 publications

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“…For the sensory parameter, we have demonstrated that gender affects sensory nerve amplitude for the median and ulnar nerves, as was demonstrated by others [3,10]. Arm length has no effect on nerve conduction velocity, in contrast to the influence of leg length and height on nerve conduction study of the leg [14][15][16].…”

Section: Discussionmentioning

confidence: 59%

Normative Data of Nerve Conduction Studies in the Upper Limb in Kuwait: Are They Different from the Western Data?

Shehab¹

1998

Med Princ Pract

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Objective: To establish the normal electrophysiological data for the median, ulnar and radial nerves and to compare our results with the Western data published in the literature. Methods: Nerve conduction studies were performed prospectively in the upper limbs of 50 carefully screened healthy individuals between the ages of 16 and 56 years using standardized technique. Results: The median motor distal latency (DL) was 3.1 (0.3) ms, amplitude 11.01 (2.8) mV, conduction velocity (CV) 56.5 (3.5) m/s. The ulnar motor studies gave DL of 2.4 (0.3) ms, amplitude 9.2 (2.2) mV, CV 60.4 (5.0) m/s. Sensory studies for the median nerve were: DL of 2.3 (0.3) ms, amplitude 63.3 (18.9) µV for men and 79.3 (28.8) µV for women and CV 56.6 (7.6) m/s. For the ulnar nerve (DL) 2.0 (0.23) ms, amplitude 54.5 (18.4) µV for men and 63.9 (16.8) µV for women and CV 51.7 (5.3) m/s. The radial sensory studies were DL 1.95 (0.3) ms, amplitude 18.7 (5.5) µV and CV 52.3 ms. Only gender showed a statistically significant effect on the sensory nerve action potential for the median (p = 0.04) and ulnar nerves (p = 0.07). Conclusion: Normative conduction parameters of commonly tested nerves in the upper limb were established in our EMG lab in Kuwait. The mean motor nerve conduction parameters for the median and ulnar nerves compare favourably with the existing literature data. However, for the sensory nerves, higher value for the nerve action potential amplitude was demonstrated in the study. Gender was shown to have a significant effect on the sensory amplitude of the median and ulnar nerves.

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Section: Discussionmentioning

confidence: 59%

Normative Data of Nerve Conduction Studies in the Upper Limb in Kuwait: Are They Different from the Western Data?

Shehab¹

1998

Med Princ Pract

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“…N1 amplitudes of CAP reflects excitability of fast-conducting myelinated axons (Fig. 8), and represents the sum of all individual action potentials (Bolton and Carter, 1980;Velumian et al, 2011). The average N1 amplitudes in CCI animals were significantly reduced compared to responses recorded in sham-operated animals ( p < 0.005; Fig.…”

Section: Corpus Callosum Compound Action Potentials (Cap) Following CCImentioning

confidence: 92%

Traumatic Brain Injury in Young Rats Leads to Progressive Behavioral Deficits Coincident with Altered Tissue Properties in Adulthood

Ajao

Pop

Adami

et al. 2012

Journal of Neurotrauma

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Traumatic brain injury (TBI) affects many infants and children, and results in enduring motor and cognitive impairments with accompanying changes in white matter tracts, yet few experimental studies in rodent juvenile models of TBI (jTBI) have examined the timeline and nature of these deficits, histologically and functionally. We used a single controlled cortical impact (CCI) injury to the parietal cortex of rats at post-natal day (P) 17 to evaluate behavioral alterations, injury volume, and morphological and molecular changes in gray and white matter, with accompanying measures of electrophysiological function. At 60 days post-injury (dpi), we found that jTBI animals displayed behavioral deficits in foot-fault and rotarod tests, along with a left turn bias throughout their early developmental stages and into adulthood. In addition, anxiety-like behaviors on the zero maze emerged in jTBI animals at 60 dpi. The final lesion constituted only *3% of brain volume, and morphological tissue changes were evaluated using MRI, as well as immunohistochemistry for neuronal nuclei (NeuN), myelin basic protein (MBP), neurofilament-200 (NF200), and oligodendrocytes (CNPase). White matter morphological changes were associated with a global increase in MBP immunostaining and reduced compound action potential amplitudes at 60 dpi. These results suggest that brain injury early in life can induce long-term white matter dysfunction, occurring in parallel with the delayed development and persistence of behavioral deficits, thus modeling clinical and longitudinal TBI observations.

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“…Age and stimulation-to-recording distance were entered as covariates because of their known effects on peripheral nerve sensory action potentials (Bolton & Carter, 1980;Horowitz & Krarup, 1992).…”

Section: Separate 2 Group (Hypertensive Normotensive) Analyses Of Comentioning

confidence: 99%

Effects of essential hypertension on short latency human somatosensory-evoked potentials

et al. 2010

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Citation: EDWARDS, L. ... et al, 2010. Effects of essential hypertension on short latency human somatosensory-evoked potentials. Psychophysiology, 47 (2), pp. 323 -331. Additional Information:• This is the peer reviewed version of the following article: EDWARDS, AbstractReduced perception of somatosensory stimulation in patients with essential hypertension may be due to deficits in the ascending somatosensory pathway.Function in the ascending somatosensory pathway was assessed by measuring N9, N13 and N20 somatosensory-evoked potentials in 14 unmedicated essential hypertensives and 22 normotensives. N9 amplitudes were smaller and N13 amplitudes marginally smaller in hypertensives than normotensives. N9 amplitudes were inversely associated with blood pressure. N20 amplitudes and N9, N13 and N20 latencies did not differ between groups. In addition, plexus-cord, cord-cortex and plexus-cortex conduction times were not different between groups. These data suggest that hypertension affects the peripheral nervous system by reducing the number of active sensory nerve fibres without affecting myelination. However, hypertension does not seem to affect the afferent somatosensory pathway within the brain.Descriptors: Arterial hypertension; Essential hypertension; Median nerve; Somatosensory evoked potentials 3

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Human sensory nerve compound action potential amplitude: variation with sex and finger circumference.

Cited by 103 publications

References 6 publications

Normative Data of Nerve Conduction Studies in the Upper Limb in Kuwait: Are They Different from the Western Data?

Normative Data of Nerve Conduction Studies in the Upper Limb in Kuwait: Are They Different from the Western Data?

Traumatic Brain Injury in Young Rats Leads to Progressive Behavioral Deficits Coincident with Altered Tissue Properties in Adulthood

Effects of essential hypertension on short latency human somatosensory-evoked potentials

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