Human T-Cell Leukaemia/Lymphoma Virus-Associated Lymphoreticular Neoplasia in Jamaica

Heterogeneous geographic distribution of human T-cell lymphotropic viruses I and II (HTLV-I/II): serological screening prevalence rates in blood donors from large urban areas in Brazil

“…Two diseases are clearly associated with HTLV-I seropositivity: adult T-cell leukemia (ATL) 5,6,7,8 and a neurological disease, HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) 9,10,11 . Other diseases have been associated with HTLV-I, for example polymyositis, polyarthritis, uveitis, and dermatological conditions 12,13 .…”

Immunoelectron microscopic localization of human T-cell leukemia virus type-I antigens.

“…Human T-cell leukemia virus type I (HTLV-I) (28) is a retrovirus etiologically associated with adult T-cell leukemia (ATL), which is endemic in southwest Japan and some other countries (2,8,19,47). HTLV-I is capable of transforming normal human T-lymphocytes (T4, helper T-cells) in vitro by cocultivation with virus-producing cells (19), but it does not contain a cell-derived oncogene.…”

Frequency of adult T-cell leukaemia/lymphoma and HTLV-I in Ibadan, Nigeria

“…In Jamaica, an HTLV-I endemic area, between 50% and 70% of all nonHodgkin's lymphoma cases are HTLV-I seropositive (Blattner et al, 1983;Gibbs et al, 1987). In Trinidad/Tobago, HTLV-I infection is restricted largely to persons of African ancestry despite the fact that the population is equally divided between persons of Asian and African origin supporting the concept that the virus is endemic in Africa (Bartholomew et al, 1985).…”