Human Thyroid Uptake and Bodily Elimination of I131 For The Case of Single and Continual Ingestion of Bound Iodine in Resin-Treated Milk

Abstract

Five human volunteers ingested resin-treated milk containing protein-bound 1131 for periods of time ranging from 1 to 63 days and in adounts ranging from 0.15 to 92 nc.In the first experiment all subjects ingested daily dosages of 1131 for periods ranging from 4 to 63 days. Thyroid uptake was measured by p r a y scintillation countings of all subjects.Urinary excretion was measured on two subjects, one of which was followed for 67 days.In a second experiment, two subjects ingested a single dose each. Thyroid uptake and urinary excretion were measured as in the first experiment. Extrapolations are made from the single-intake data to the case of continuous intake and are compared with the daily intake data.From these data, estimates are made offw,fi,fi and Tb for thyroid gland and are compared with ICRP and NCRP recommendations.