Human γγ‐Enolase: Two‐Site Immunoradiometric Assay with a Single Monoclonal Antibody

Federsppiel, B; Cras, Patrick; Gheuens, J.; Andries, Dirk; Löwenthal, A.

doi:10.1111/j.1471-4159.1987.tb13122.x

Cited by 24 publications

(9 citation statements)

References 23 publications

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“…Specimens were fixed in formalin and were processed routinely, with 4-m sections being stained with hematoxylin and eosin and PAM. The avidin-biotin complex (ABC) immunoperoxidase method was also used in conjunction with the following antibodies: proliferating cell nuclear antigen (PCNA) for staining cells in the S-phase of the cell cycle (DAKO, Glostrupp, Denmark) [11], S-100 for human S-100 A and B (DAKO) [12], NSE to identify cells of neurogenic origin (DAKO) [13], and ␣SMA for smooth muscles (DAKO) [14]. Normal skin from the surgical operation material was used as control.…”

Section: Hair Removal Proceduresmentioning

confidence: 99%

Histologic effects of ruby laser hair removal in Japanese patients

Omi

Honda²,

Yamamoto³

et al. 1999

Lasers Surg. Med.

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Section: Hair Removal Proceduresmentioning

confidence: 99%

Histologic effects of ruby laser hair removal in Japanese patients

Omi

Honda²,

Yamamoto³

et al. 1999

Lasers Surg. Med.

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“…They did not increase in any particular neu rological disease. In 3 cases of AD the results were within the normal range [Soler Federsppiel et al, 1987], (5) Neurofilament proteins were deter mined in 50 CSF samples. Normal values seem to be lower than 3.5 ng/ml.…”

Section: Resultsmentioning

confidence: 99%

“…The determinations of SI00 , MBP , yy-enolase [Soler Federsppiel et al, 1987] did not yield complementary diagnostic informa tion. Neurofilament proteins were increased in CSF of different neurological diseases and of 2 cases of familial AD.…”

Section: Discussionmentioning

confidence: 99%

Blood and Cerebrospinal Fluid Anomalies in Brain Ageing and Alzheimer's Disease

Federsppiel¹,

Karcher²,

Löwenthal³

1987

Gerontology

Self Cite

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The glial fibrillary acidic protein (GFAP), myelin basic protein (MBP), S100 protein (S100), ΓΓ-enolase and neurofilament proteins were determined in the CSF of neurological patients. In Alzheimer’s disease (AD), the GFAP values were very often increased but this was not specific to this disease. In 2 cases of familial AD, increases in neurofilament protein were detected. The determination of autoantibodies against neurofilament proteins in blood showed rather low values in AD, although they were higher than in subacute sclerosing panencephalitis (SSPE) and Chagas’ disease. Increases were observed in diseases not related to AD such as vascular disorders and Parkinson’s disease.

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“…We used enolase 2 (NSE, gamma neuronal), also known as ENO2. This isoenzyme is a homodimer found in mature neurons and cells of neuronal origin 8. Sixty formalin-fixed and paraffin-embedded tissue sections with the most representative hot spot triangular chiral mirror geometry complex areas were analyzed using neuron-specific enolase antibody marker.…”

Section: Neuron-specific Enolase Immunostainmentioning

confidence: 99%

Intercellular cancer collisions generate an ejected crystal comet tail effect with fractal interface embryoid body reassembly transformation

Diaz

Murillo

Barrero³

2011

CMR

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We have documented self-assembled geometric triangular chiral crystal complexes (GTCHC) and a framework of collagen vascular invariant geometric attractors in cancer tissues. This article shows how this system evolves in time. These structures are incorporated together and evolve in different ways. When the geometric core is stable, and the tissue architecture collapses, fragmented components emerge, which reveal a hidden interior identifying how each molecule is reassembled into the original mold, using one common connection, ie, a fractal self-similarity that guided the system from the beginning. GTCHC complexes generate ejected crystal comet tail effects and produce strange helicity states that arise in the form of spin domain interactions. As the crystal growth vibration stage progresses, biofractal echo images converge in a master-built construction of embryoid bodies with enolase-selective immunopositivity in relation to clusters of triangular chiral cell organization. In our electro-optic collision model, we were able to predict and replicate all the characteristics of this complex geometry that connects a physical phenomenon with the signal patterns that generate biologic chaos. Intrinsically, fractal geometry makes spatial correction errors embrace the chaotic system in a way that permits new structures to emerge, and as a result, an ordered self-assembly of embryoid bodies with neural differentiation at the final stage of cancer development is a predictable process. We hope that further investigation of these structures will lead not only to a new way of thinking about physics and biology, but also to a rewarding area in cancer research.

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Human γγ‐Enolase: Two‐Site Immunoradiometric Assay with a Single Monoclonal Antibody

Cited by 24 publications

References 23 publications

Histologic effects of ruby laser hair removal in Japanese patients

Histologic effects of ruby laser hair removal in Japanese patients

Blood and Cerebrospinal Fluid Anomalies in Brain Ageing and Alzheimer's Disease

Intercellular cancer collisions generate an ejected crystal comet tail effect with fractal interface embryoid body reassembly transformation

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