Humoral immune response to pneumococcal vaccination

Konradsen, Helle Bossen

doi:10.1111/j.1600-0463.1996.tb05577.x

Cited by 7 publications

(3 citation statements)

References 75 publications

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“…Estimates of the levels of PCV7 use between 2001 and 2006 range from 0.6 to 1.4 doses per 1,000 children [5]. The 23-valent polysaccharide vaccine (PPV23) has been recommended for people aged у65 years and those aged 2-64 years with certain high-risk conditions since 1996 [16]. The estimated level of PPV23 use has declined from ∼30 to 17 doses per 1,000 persons aged у65 years between 1998 and 2007 [5] (estimates based on the number of vaccines sold in Denmark, unpublished data from Statens Serum Institut, Sales and Development Department, and the Danish Medicines Agency [17]).…”

Section: Methodsmentioning

confidence: 99%

Temporal Trends in Invasive Pneumococcal Disease and Pneumococcal Serotypes over 7 Decades

Harboe¹,

Benfield²,

et al. 2010

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Section: Methodsmentioning

confidence: 99%

Temporal Trends in Invasive Pneumococcal Disease and Pneumococcal Serotypes over 7 Decades

Harboe¹,

Benfield²,

et al. 2010

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“…The currently available pneumococcal vaccine consists of polysaccharides from the 23 most commonly found serogroups/serotypes, covering 90% of the types isolated from invasive infections [3–5]. Unfortunately, the vaccine is not protective in children under 2 years old.…”

Section: Introductionmentioning

confidence: 99%

“…Unfortunately, the vaccine is not protective in children under 2 years old. Protein‐conjugated vaccines stimulating the T‐cell response are under development [2,3]. Epidemiologic studies of the serotype distribution and antibiotic resistance are necessary in order to know the probable efficacy of a vaccine in a particular area [6].…”

Section: Introductionmentioning

confidence: 99%

Serotyping and antibiotic resistance of Streptococcus pneumoniae isolated from pediatric infections in central Greece

Kouppari

Zaphiropoulou

Tsolia

et al. 1998

Clinical Microbiology and Infection

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OBJECTIVE: To determine the distribution of serogroups/serotypes and antibiotic resistance pattern of Streptococcus pneumoniae isolated from pediatric infections in central Greece. METHODS: In total, 306 S. pneumoniae strains isolated from children, aged from 18 days to 14 years (median 18 months), during a 21-month period, from different specimen sources, were studied. Susceptibility testing was carried out by the Kirby---Bauer method and by the Etest, and serotyping by the Quellung reaction. RESULTS: Of the S. pneumoniae isolates, 3.9% were highly resistant to penicillin (PR), while 17.6% were intermediately resistant (IPR). PR and IPR isolates were found to be, in general, more resistant to other antibiotics than penicillin-susceptible isolates. The PR and IPR isolates belonged to the serogroup/serotypes 19, 23, 9, 6 and 14 (in descending order of frequency). The penicillin-susceptible isolates belonged to 20 different groups/serotypes, the most common being 19, 6, 14, 9, 3, 23 and 1 (in descending order of frequency). Serogroup 23 was often found to be multiresistant. CONCLUSIONS: Resistance to penicillin in S. pneumoniae isolates is relatively low and differs according to the specimen type. All the pneumococcal serogroups/serotypes isolated from the children were found to be included in the 23-valent polysaccharide vaccine. Most of the children with a pneumococcal infection, however, were less than 2 years old and could not be protected by the existing vaccine.

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Laparoscopic Splenectomy for Malignant Diseases

Heniford¹,

Walsh²

2001

Minimally Invasive Cancer Management

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Humoral immune response to pneumococcal vaccination

Cited by 7 publications

References 75 publications

Temporal Trends in Invasive Pneumococcal Disease and Pneumococcal Serotypes over 7 Decades

Temporal Trends in Invasive Pneumococcal Disease and Pneumococcal Serotypes over 7 Decades

Serotyping and antibiotic resistance of Streptococcus pneumoniae isolated from pediatric infections in central Greece

Laparoscopic Splenectomy for Malignant Diseases

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