Humoral immune responses following experimental infection of goats with Mycoplasma capricolum subsp. capripneumoniae

March, John B.; Harrison, J. C.; Borich, S. M.

doi:10.1016/s0378-1135(01)00434-5

Cited by 20 publications

(29 citation statements)

References 27 publications

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“…However, the current prevalence is lower than other studies in the country (Gezahegn 1993;Bereket 1995;Sharew et al 2005). One of the reasons for this could be the low seroprevalence of CFT, which might be related to the ability of the test to detect antibody that appear first and span short duration in the blood which could be due to the limitations of CFT as observed by March et al (2002). March et al (2002), did not observe significant CFT titres in infected goats 21 days post infection.…”

Section: Discussionmentioning

confidence: 68%

“…One of the reasons for this could be the low seroprevalence of CFT, which might be related to the ability of the test to detect antibody that appear first and span short duration in the blood which could be due to the limitations of CFT as observed by March et al (2002). March et al (2002), did not observe significant CFT titres in infected goats 21 days post infection. Therefore, at an early stage in a field outbreak, false negative results based upon serological diagnosis are a real possibility as observed in Shabba PA where only few positive cases detected by CFT test despite the presence of clinical cases of CCPP.…”

Section: Discussionmentioning

confidence: 99%

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Participatory investigation of Contagious Caprine Pleuropneumonia (CCPP) in goats in the Hammer and Benna-Tsemay districts of southern Ethiopia

Mekuria

Zerihun

Gebreegziabher

et al. 2008

Trop Anim Health Prod

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The study was conducted in two selected districts of Southern Omo zones of Ethiopia, namely Hammer and Benna-Tsemay, during November 2004 and May 2005 to determine the status of contagious caprine pleuropneumonia (CCPP). Participatory disease investigation was conducted in the goat flocks owned by pastoralists of the districts. Participatory methods such as proportionate piling and matrix scoring of diseases were used to characterise major diseases of goats. Clinical and post-mortem examinations and isolation of the causative agent of CCPP were done. Serological tests were conducted using CFT. CCPP (locally termed Sompo) ranked as the first important disease of goats in the study area. Local perception of causes and signs of CCPP were described. Matrix scoring between groups revealed that disease signs and causes showed weak, moderate and good agreement by Kendall's coefficient concordance (W = 0.21-0.99). The overall sero-prevalence of CCPP was 15.5%. The causative agent was isolated from sick animals in the lab. The characteristic clinical signs, gross lesions, bacteriological isolation of the causative agent supported by participatory epidemiological disease investigation revealed that CCPP is a major disease of goats in the study districts. Participatory epidemiology using indigenous knowledge could efficiently be used to generate sufficient information with minimum cost, local materials and within reasonably short period of time, assisting the designing of feasible disease control programme in developing countries.

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Section: Discussionmentioning

confidence: 68%

Section: Discussionmentioning

confidence: 99%

Participatory investigation of Contagious Caprine Pleuropneumonia (CCPP) in goats in the Hammer and Benna-Tsemay districts of southern Ethiopia

Mekuria

Zerihun

Gebreegziabher

et al. 2008

Trop Anim Health Prod

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“…Other researchers pointed at the importance of the complement fixation titer, as an amplifier of the humoral immune responses (March et al 2002;Wesonga et al 2004;Castro et al 2008), which will help the animal to overcome the invading pathogens by a cascade of enzymatic reactions performed by the C1-C9 complements (Rao 2006;Castro et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Preliminary comparison of different immune and production components in local and imported Saanen goats reared under a sub-tropical environment

Barbour

Itani

Sleiman

et al. 2011

Trop Anim Health Prod

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Three objectives were included in this research work. The first objective compared different immune components in healthy mature males, mature females, and female kids of local and imported Saanen goats, reared under a sub-tropical environment. The significantly differing immune components were the blood monocyte percent, blood CD8 count, and the total white blood cell count. The second objective compared the performance of Saanen versus local does. The means of the milk yield and prolificacy of the imported Saanen does were significantly higher than those of the local does (p<0.05). The third objective compared the immune responses (hemagglutination-HA titers) and complement fixation (CF) titers in mature does of the two breeds to chicken red blood cells (c-RBC). The HA titers showed a significant seroconversion only in imported Saanen (p<0.05) but not in local does; however, the CF titers increased significantly at 4 weeks following priming with c-RBC in local (p<0.05) but not in the imported Saanen does. The impact of the differences in blood immune components and responses to antigens in the compared goats on protection potential against prevalent diseases in the sub-tropical zone of the eastern Mediterranean countries is discussed.

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“…In primary infected goats, CCPP last for about two days with high mortality (McMartin et al 1980) while in other cases it may last for several days (OIE 2009). However, in the experimental infection model of March et al (2002), Mccp was not isolated from the infected lungs of goats (eight week post infection) due to the development of humoral immunity (IgG, IgM).…”

Section: Incubation Period Of Mycoplasma Capricolum Subsp Capripneummentioning

confidence: 99%

Contagious caprine pleuropneumonia and its current picture in Pakistan: a review

Samiullah¹

2013

Vet. Med. - Czech

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Contagious caprine pleuropneumonia (CCPP) is caused by Mycoplasma capricolum subsp. capripneumoniae (Mccp) which belongs to the Mycoplasma mycoides cluster, a group of five closely related Mycoplasmas, pathogenic to ruminants. The true lesions of CCPP are restricted to the alveolar tissues of infected goats, which distinguish it from other respiratory diseases of small ruminants caused by members of the Mycoplasma mycoides cluster. The typical signs of CCPP are an accumulation of pleural fluid, unilateral hepatisation, adhesions, pleurisy and pleuropneumonia which clearly differentiate it from "MAKePS" syndrome caused by Mycoplasma mycoides subsp. capri (Mmc). The available literature on CCPP shows that so far in Pakistan, the true causative agent (Mccp) of this disease has only been isolated in the Pashin District of Balochistan and that the disease is more frequently confused with other respiratory diseases of goat caused by the Mycoplasma mycoides cluster. The lack of suitable techniques and extensive knowledge in the field is a big limitation for the isolation and characterisation of Mccp from prevailing CCPP-like cases in the goat population of Pakistan.

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Humoral immune responses following experimental infection of goats with Mycoplasma capricolum subsp. capripneumoniae

Cited by 20 publications

References 27 publications

Participatory investigation of Contagious Caprine Pleuropneumonia (CCPP) in goats in the Hammer and Benna-Tsemay districts of southern Ethiopia

Participatory investigation of Contagious Caprine Pleuropneumonia (CCPP) in goats in the Hammer and Benna-Tsemay districts of southern Ethiopia

Preliminary comparison of different immune and production components in local and imported Saanen goats reared under a sub-tropical environment

Contagious caprine pleuropneumonia and its current picture in Pakistan: a review

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