Hundreds of basal cell carcinomas in a Gorlin‐Goltz syndrome patient cured with imiquimod 5% cream

Abstract

877 6 Jones EW, Heyl T. Naevus sebaceus. A report of 140 cases with special regard to the development of secondary malignant tumours. Br J Dermatol 1970; 82: 99-117. 7 Domingo J, Helwig EB. Malign neoplasms associated with nevus sebaceus of Jadassohn. J Am Acad Dermatol 1979; 1: 545-556. 8 Tarkhan II, Domingo J. Metastasizing eccrine porocarcinoma developing in a sebaceous nevus of Jadassohn. Report of a case. Arch Dermatol 1985; 121: 413-415. 9 Yeatman JM, Kilkenny M, Marks R. The prevalance of seborrheic keratoses in an Australian population: does exposure to sunlight play a part in their frequency? Br J Dermatol 1997; 137: 411-414. 10 Misago N, Satoh T, Narisawa Y. Basal cell carcinoma with tricholemmal (at the lower portion) differantiation within seborrheic keratosis.

Gorlin-Goltz syndrome – a medical condition requiring a multidisciplinary approach

“…– used for treatment of the nodular basal cell carcinomas alone or in association with curettage; the therapy involves 5 applications of the cream in a week and lasts 6 weeks [10,43,46]…”

Naevoid Basal Cell Carcinoma Syndrome in a 22-month-old Child Presenting with Multiple Basal Cell Carcinomas and a Fetal Rhabdomyoma

“…other treatments such as laser ablation, photodynamic therapy, and topical chemotherapy may be effective in patients with multiple lesions (10). Imiquimod 5% cream also seems to be useful (11). Total body application of topical 0.1% tretinoin cream, has been successfully used in patients with superficial BCCs (12).…”

“ PTCH ”-ing It Together: A Basal Cell Nevus Syndrome Review

“…There are case reports of imiquimod use in BCNS . Three individuals with BCNS used imiquimod three times per week for 6–8 weeks on the face, extremities, and trunk.…”