2023
DOI: 10.3390/ph16111513
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Huntington’s Disease Drug Development: A Phase 3 Pipeline Analysis

Hannah J. Van de Roovaart,
Nguyen Nguyen,
Timothy D. Veenstra

Abstract: Huntington’s Disease (HD) is a severely debilitating neurodegenerative disorder in which sufferers exhibit different combinations of movement disorders, dementia, and behavioral or psychiatric abnormalities. The disorder is a result of a trinucleotide repeat expansion mutation that is inherited in an autosomal dominant manner. While there is currently no treatment to alter the course of HD, there are medications that lessen abnormal movement and psychiatric symptoms. ClinicalTrials.gov was searched to identify… Show more

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Cited by 8 publications
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