Ocean-atmosphere interactions before and after the passage of Typhoons Haitang, Fung-wong, and Morakot across the southern region of the East China Sea (ECS) were examined by assessing satellite measurements of sea surface temperature (SST) and chlorophyll-a (chl-a) concentration in conjunction with wind data. In terms of the satellite-derived data, the SST declined and chl-a concentration increased after the passage of the typhoons, and this could have resulted from the upwelling induced by typhoons via their long-duration, strong winds. According to fisheries data collected after the passing of Typhoon Morakot, the major fishing grounds of the torchlight fishery were found to have shifted northwards from the northern tip of Taiwan to the southern ECS. Moreover, the major target fish species changed from skipjack tuna (pre-typhoon) to squid (post-typhoon), signifying that the typhoon-enhanced upwelling might have caused the skipjack tuna, which typically prefer warm water, to have migrated elsewhere. In contrast, the nutrient-rich, upwelled water might have directly led to increases in chl-a concentrations and contributed the increase in local squid densities. This study suggests that typhoons can cause marked cooling of the sea surface as well as enhance upwelling that previously resulted in not only chl-a increases but also changes of local fish communities and, consequently, fishing activities.