2018
DOI: 10.1159/000490854
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Hürthle Cell Carcinoma in a Lingual Thyroid

Abstract: Objective: To present a case of lingual thyroid Hürthle cell carcinoma (HCC). Clinical Presentation and Intervention: A 37-year-old female presented with dysphagia and recurrent haemorrhage. Histopathology was suggestive of HCC; the tumour was excised by the trans-glossal approach which provided adequate exposure and helped avert external scarring or mandibular osteotomy. Histopathology showed a tumour-positive right lateral resection margin. This prompted referral to nuclear medicine for radio-iodine ablation… Show more

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Cited by 5 publications
(3 citation statements)
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“…Unlike squamous cell carcinoma, which displays submucosal infiltration that may be difficult to evaluate macroscopically, lingual thyroid is more likely to be exophytic rather than ulcerous, and TC was more often described as encapsulated tumors or microscopic foci that developed in lingual thyroid in our literature review. 7,12,16,18 -20,22-23,26,28,30,32 -38,44,50 Another serious issue concerning the TORS procedure is that surgical assessment of the neck and total thyroidectomy in cases of thyroid cancer and/or multiple ectopic glands may be limited, although such techniques have been described by some authors. 12,54,55 Indeed, in their literature review, Stokes et al highlighted that a significant proportion of patients (3/7) who underwent a transoral procedure for follicular carcinoma in LT, were shown to have persistent disease in the neck or primary site, and later required additional surgery.…”
Section: Discussionmentioning
confidence: 99%
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“…Unlike squamous cell carcinoma, which displays submucosal infiltration that may be difficult to evaluate macroscopically, lingual thyroid is more likely to be exophytic rather than ulcerous, and TC was more often described as encapsulated tumors or microscopic foci that developed in lingual thyroid in our literature review. 7,12,16,18 -20,22-23,26,28,30,32 -38,44,50 Another serious issue concerning the TORS procedure is that surgical assessment of the neck and total thyroidectomy in cases of thyroid cancer and/or multiple ectopic glands may be limited, although such techniques have been described by some authors. 12,54,55 Indeed, in their literature review, Stokes et al highlighted that a significant proportion of patients (3/7) who underwent a transoral procedure for follicular carcinoma in LT, were shown to have persistent disease in the neck or primary site, and later required additional surgery.…”
Section: Discussionmentioning
confidence: 99%
“…Of the 373 peer-reviewed articles found, 96 were assessed for eligibility. Finally, 40 reports provided adequate information on surgical management and outcomes for patients with LT 7,12,15,16,18 -51 (Figure 3). The majority were case reports and 6 were case series with a maximum of 6 patients, for a total of 61 patients, including our case.…”
Section: Literature Review Of Surgical Treatments For Lt and Specific Outcomesmentioning
confidence: 99%
“…Long term follow-up of these patients is recommended as there have been reports of malignant transformation, although this is rare 10 .…”
Section: Discussionmentioning
confidence: 99%