Hyaluronic acid injection to restore the lost interproximal papilla: a systematic review

Castro-Calderón, Adriana; Roccuzzo, Andrea; Ferrillo, Martina; Gada, Sneha; González‐Serrano, José; Fonseca, Manrique; Molinero‐Mourelle, Pedro

doi:10.1080/00016357.2021.2007282

Cited by 13 publications

(9 citation statements)

References 30 publications

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“…In addition, periodontal surgery is used when the depth of the periodontal pockets prevents adequate access for debridement. After causal therapy, a supportive periodontal therapy is employed to reduce the probability that the disease will flare up again, thus maintaining teeth without pain, excessive mobility, or persistent infection [ 225 , 226 , 227 ]. According to the American Academy of Periodontology, supportive periodontal therapy should include a periodontal re-evaluation and risk assessment, supragingival and subgingival removal of bacterial plaque and calculus, and re-treatment of any sites showing recurrent or persistent disease [ 225 ].…”

Section: Oral Health Management For Older Subjectsmentioning

confidence: 99%

Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review

et al. 2022

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Frailty is a highly prevalent condition in the elderly that has been increasingly considered as a crucial public health issue, due to the strict correlation with a higher risk of fragility fractures, hospitalization, and mortality. Among the age-related diseases, sarcopenia and dysphagia are two common pathological conditions in frail older people and could coexist leading to dehydration and malnutrition in these subjects. “Sarcopenic dysphagia” is a complex condition characterized by deglutition impairment due to the loss of mass and strength of swallowing muscles and might be also related to poor oral health status. Moreover, the aging process is strictly related to poor oral health status due to direct impairment of the immune system and wound healing and physical and cognitive impairment might indirectly influence older people’s ability to carry out adequate oral hygiene. Therefore, poor oral health might affect nutrient intake, leading to malnutrition and, consequently, to frailty. In this scenario, sarcopenia, dysphagia, and oral health are closely linked sharing common pathophysiological pathways, disabling sequelae, and frailty. Thus, the aim of the present comprehensive review is to describe the correlation among sarcopenic dysphagia, malnutrition, and oral frailty, characterizing their phenotypically overlapping features, to propose a comprehensive and effective management of elderly frail subjects.

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Section: Oral Health Management For Older Subjectsmentioning

confidence: 99%

Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review

et al. 2022

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“…Hyaluronic acid (HA), an anionic, non-sulfated glycosaminoglycan and a major component of the extracellular matrix in most tissues, is being used in various regenerative medical and tissue engineering approaches [ 15 ]. Recently, it has been studied as a possible adjacent treatment in periodontal [ 16 ] and implant surgery [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Adjunctive use of hyaluronic acid in the treatment of gingival recessions: a systematic review and meta-analysis

Kalimeri,

Roccuzzo,

Stähli

et al. 2024

Clin Oral Invest

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Objectives To explore the efficacy of Hyaluronic acid as an adjunctive in treatment of gingival recessions (GR). Materials and methods A systematic literature search was performed in several electronic databases, including Medline/ PubMed, Embase, CENTRAL and LILACS. Recession improvement was evaluated through multiple outcome variables. The Cochrane Risk of Bias tool and the ROBINS-I tool were used to assess the quality of the included trials. Weighted Mean Differences (WMDs) and 95% confidence intervals (CIs) between test and control sites were estimated through meta-analysis using a random-effect model for the amount of Relative Root Coverage (RRC). Results A total of 3 randomised studies were deemed as eligible for inclusion. Their data were also used for pooling the effect estimates. Overall analysis of RRC (3 studies) presented a WMD of 7.49% (p = 0.42; 95% CIs -10.88, 25.86) in favour of adjunctive use of hyaluronic acid during Coronally Advanced Flap (CAF) technique, although statistical significance was not reached. Statistical heterogeneity was found to be high (I2 = 80%). Conclusions Within their limitations, the present data indicate that the local application of Hyaluronic acid does not lead to additional clinical benefits when used as an adjunctive to the treatment of GR with CAF. However, due to the high heterogeneity among the studies, additional well-designed RCTs are needed to provide further evidence on this clinical indication for the use of Hyaluronic acid. Clinical relevance In the frame of the current review, the adjunctive use of Hyaluronic acid does not additionally improve the clinical outcomes obtained during treatment of GR with CAF.

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“…To counter these problems a few treatment modalities can be employed that can solve these complications occurred by GR. [ 6 , 7 ] Some studies have shown some association/relationship between the gingival biotype (i.e., the thickness of the gingiva) and the occurrence of GR. [ 1 , 2 , 4 ] As mentioned earlier, the thick gingiva biotype is associated with good periodontal health and the ability to resist trauma and recession.…”

Section: Introductionmentioning

confidence: 99%

Correlation between Gingival Thickness and Occurrence of Gingival Recession

Koppolu,

Al Arabi,

Al Khayri

et al. 2023

Journal of Pharmacy and Bioallied Sciences

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Background: Gingival recession (GR) has become a common problem among patients. GR is associated with increased accumulation of plaque, root caries, abrasion and cervical wear, and dentinal hypersensitivity. The present study aimed to examine the correlation between gingival biotypes and the occurrence of GR. Methods: The study initially recruited 94 subjects; however, 54 of them did not have any recession sites, and hence were discarded. Therefore, the analysis was performed on 40 subjects. The study particularly compared the relationship between the recession length (RL) and width along with the gingival thickness (GT). As such, different clinical parameters were analyzed, namely, RL, recession width (RW), keratinized gingival width (KGW), and GT. Results: Based on the statistical analysis (descriptive statistics and Pearson’s correlation) conducted on the collected data, the study established that the gingival RL has a significant negative relationship with GT, which implied that the amount of thickness is inversely proportional to the RL. The study also found a significant positive correlation between RW and RL as well as between GT and KGW. Conclusion: Based on the findings, the study thus concluded that the gingival biotype (thickness) significantly determines the occurrence and extent of GR.

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Hyaluronic acid injection to restore the lost interproximal papilla: a systematic review

Cited by 13 publications

References 30 publications

Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review

Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review

Adjunctive use of hyaluronic acid in the treatment of gingival recessions: a systematic review and meta-analysis

Correlation between Gingival Thickness and Occurrence of Gingival Recession

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