Cardiovascular diseases (CVDs) remain a global burden, highlighting the need for innovative approaches for early detection and intervention. This study investigates the potential of deep learning, specifically convolutional neural networks (CNNs), to improve the prediction of heart disease risk using key personal health markers. Our approach revolutionizes traditional healthcare predictive modeling by integrating CNNs, which excel at uncovering subtle patterns and hidden interactions among various health indicators such as blood pressure, cholesterol levels, and lifestyle factors. To achieve this, we leverage advanced neural network architectures. The model utilizes embedding layers to transform categorical data into numerical representations, convolutional layers to extract spatial features, and dense layers to model complex interactions and predict CVD risk. Regularization techniques like dropout and batch normalization, along with hyperparameter optimization, enhance model generalizability and performance. Rigorous validation against conventional methods demonstrates the model’s superiority, with a significantly higher R2 value of 0.994. This achievement underscores the model’s potential as a valuable tool for clinicians in CVD prevention and management. The study also emphasizes the need for interpretability in deep learning models and addresses ethical considerations to ensure responsible implementation in clinical practice.