Hybrid chemoenzymatic heterogeneous catalysts

Debecker, Damien P.; Smeets, Valentin; Verren, Margot Van der; Arango, Hippolyte Meersseman; Kinnaer, Marty; Devred, François

doi:10.1016/j.cogsc.2020.100437

Cited by 26 publications

(26 citation statements)

References 38 publications

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“…divinylbenzene dioxide [286,287] ) used in epoxy resins. Also, pristine chemical space could be explored – also in the field of epoxidation – with the help of hybrid chemo‐enzymatic heterogeneous catalysts [288] . While a first example of hybrid chemo‐enzymatic heterogeneous catalysis was recently reported for the epoxidation of allyl alcohol using in‐situ generated hydrogen peroxide, [191] we suggest that the most relevant developments that can be expected is in the field of organic synthesis towards high added‐value – possibly chirally pure – chemicals.…”

Section: Conclusion and Prospectsmentioning

confidence: 90%

Titanosilicate Epoxidation Catalysts: A Review of Challenges and Opportunities

2021

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Epoxidation reactions are tremendously important for modern chemistry, as they lead to series of highly useful bulk and fine chemicals, monomers, and intermediates for organic synthesis. Progress in epoxidation processes goes hand in hand with the advancement made in catalysis science. In this context, heterogeneous catalysts, and particularly Ti‐based formulations, are playing a central role and have seen tremendous developments over the past two decades, leveraging on advanced materials science. The aim of this review is to illustrate the various strategies of titanosilicate catalysts preparation that can lead to more versatile, more performant, and greener epoxidation processes. We successively cover (i) supported catalysts, obtained by the grafting of Ti species onto preformed silica supports, (ii) microporous crystalline titanosilicates (zeolites), and (iii) amorphous titanosilicates obtained by sol‐gel chemistry. For each category, with an emphasis on catalyst preparation, the challenges that have to be tackled to boost catalyst performance are highlighted. From that point, we present a critical review of the different approaches that have been proposed in the primary literature to tailor the properties that govern catalysts performance (activity, selectivity, stability, ease of handling). This is done by better controlling the nature of the active surface species, adapting particles size and shape, optimizing texture, modifying surface chemistry, etc. These lines of attack encompass molecular approaches for the grafting of well‐defined species, top‐down and bottom‐up synthesis of hierarchically porous zeolites, advanced sol‐gel routes potentially performed in non‐conventional media or coupled with original processing, preparation of self‐standing monoliths, etc. Future research directions are discussed with emphasis on the application scope of new catalytic materials and possible approaches to increase catalyst performance.

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Section: Conclusion and Prospectsmentioning

confidence: 90%

Titanosilicate Epoxidation Catalysts: A Review of Challenges and Opportunities

2021

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“…Advantageously, the enzyme can be immobilized on a carrier to facilitate recovery and reuse. Even more interestingly, the two catalytic species can be combined in a unique bifunctional solid 18–21 by immobilizing the enzyme directly onto an active solid catalyst, to form a so-called “hybrid chemoenzymatic heterogeneous catalyst” (HCEHC). 5,18,22–24 The latter materials are designed to host at least two catalytic active species – a chemical one and an enzymatic one – and to be easily separated from the reaction medium (and potentially reused).…”

Section: Introductionmentioning

confidence: 99%

Hybrid chemoenzymatic heterogeneous catalyst prepared in one step from zeolite nanocrystals and enzyme–polyelectrolyte complexes

et al. 2021

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“…For instance, co-immobilization can bring different (bio)catalysts in close proximity, thus avoiding diffusion of intermediates to the reaction media bulk, in a similar way to natural biochemical cascades, and allows for synergetic effects between catalysts. Conversely, coimmobilization of enzymes and chemocatalysts can offer compartmentalization strategies to overcome incompatibility issues [15,16,[24][25][26]. Co-immobilization of (bio)catalysts is a promising but also challenging field whose advances might come from multidisciplinary efforts involving areas such as chemistry, biology, and material sciences.…”

Section: Introductionmentioning

confidence: 99%

Multicatalytic Hybrid Materials for Biocatalytic and Chemoenzymatic Cascades—Strategies for Multicatalyst (Enzyme) Co-Immobilization

et al. 2021

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During recent decades, the use of enzymes or chemoenzymatic cascades for organic chemistry has gained much importance in fundamental and industrial research. Moreover, several enzymatic and chemoenzymatic reactions have also served in green and sustainable manufacturing processes especially in fine chemicals, pharmaceutical, and flavor/fragrance industries. Unfortunately, only a few processes have been applied at industrial scale because of the low stabilities of enzymes along with the problematic processes of their recovery and reuse. Immobilization and co-immobilization offer an ideal solution to these problems. This review gives an overview of all the pathways for enzyme immobilization and their use in integrated enzymatic and chemoenzymatic processes in cascade or in a one-pot concomitant execution. We place emphasis on the factors that must be considered to understand the process of immobilization. A better understanding of this fundamental process is an essential tool not only in the choice of the best route of immobilization but also in the understanding of their catalytic activity.

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Hybrid chemoenzymatic heterogeneous catalysts

Cited by 26 publications

References 38 publications

Titanosilicate Epoxidation Catalysts: A Review of Challenges and Opportunities

Titanosilicate Epoxidation Catalysts: A Review of Challenges and Opportunities

Hybrid chemoenzymatic heterogeneous catalyst prepared in one step from zeolite nanocrystals and enzyme–polyelectrolyte complexes

Multicatalytic Hybrid Materials for Biocatalytic and Chemoenzymatic Cascades—Strategies for Multicatalyst (Enzyme) Co-Immobilization

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