The development of biomedical devices benefits patients by offering real-time healthcare. In particular, pacemakers have gained a great deal of attention because they offer opportunities for monitoring the patient’s vitals and biological statics in real time. One of the important factors in realizing real-time body-centric sensing is to establish a robust wireless communication link among the medical devices. In this paper, radio transmission and the optimal characteristics for impedance matching the medical telemetry of an implant are investigated. For radio transmission, an integral coupling formula based on 3D vector far-field patterns was firstly applied to compute the antenna coupling between two antennas placed inside and outside of the body. The formula provides the capability for computing the antenna coupling in the near-field and far-field region. In order to include the effects of human implantation, the far-field pattern was characterized taking into account a sphere enclosing an antenna made of human tissue. Furthermore, the characteristics of impedance matching inside the human body were studied by means of inherent wave impedances of electrical and magnetic dipoles. Here, we demonstrate that the implantation of a magnetic dipole is advantageous because it provides similar impedance characteristics to those of the human body.