Hybrid forward-peaked-scattering-diffusion approximations for light propagation in turbid media with low-scattering regions

Hybrid model of light propagation in random media based on the time-dependent radiative transfer and diffusion equations

“…Alternative models for the accurate and efficient calculation of light propagation have also been proposed [9,10,11,12,13,14], and among these a hybrid model based on the RTE and DE is one of the most promising approaches. Tarvanien et al have proposed the hybrid model in frequency domain [10,11,12], and Gorpas et al have applied this model to fluorescence imaging [13,14]. It has been successfully shown that the light propagation calculated from this model is in good agreement with the RTE calculations.…”

Time-Domain Near-Infrared Spectroscopy and Imaging: A Review

“…Software for the two-layered finite cylinders is given in the Reference [32] (pp. [109][110][111][112][113][114][115][116][117][118][119][120][121][122][123][124][125].…”

“…In the fields of DOT and fluorescence diffuse optical tomography (FT) for small animals and small organs like human fingers and teeth, the early-time regime plays an important role, and simple application of the DE may be inappropriate. Several hybrid models have been proposed for CW [116], FD [117,118], and TD [119][120][121]. In the FD version of the coupled RTE-DE model [117], the whole computation domain is divided into two subdomains of near-field regions using the RTE and far-field regions using the DE, and the continuity of the intensity and its derivatives at the interface between the two subdomains are given for connecting the solutions of the RTE and DE.…”

Hybrid radiosity-SP3 equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions

“…Hybrid radiosity-SP 3 To provide an ideal solution for a specific problem of gastric cancer detection in which lowscattering regions simultaneously existed with both the non-and high-scattering regions, a novel hybrid radiosity-SP 3 equation based reconstruction algorithm for bioluminescence tomography was proposed in this paper. In the algorithm, the third-order simplified spherical harmonics approximation (SP 3 ) was combined with the radiosity equation to describe the bioluminescent light propagation in tissues, which provided acceptable accuracy for the turbid medium with both low-and non-scattering regions.…”

“…Non-scattering regions would be of great impact on the quality of reconstructed images if they were not considered in the forward light transport model for three-dimensional (3D) optical imaging. [1][2][3] In previous studies, a hybrid radiosity-diffusion model (HRDM) and the related reconstruction algorithm were provided for diffuse optical tomography and bioluminescence tomography (BLT) and were successfully applied to determining the level of oxygenated blood within the brain and detecting gastric cancer in vivo in which the cerebrospinal fluid around the brain and the stomach were modeled as the non-scattering regions. 4,5 The goal of BLT is to reconstruct the 3D distribution of the targeted bioluminescent probes by integrating multi-view two-dimensional bioluminescent images, geometrical structures, and tissues' optical properties on the basis of an accurate light transport model.…”