Hybrid Parallelization of a Large-Scale Heart Model

Science at LLNL with IBM Blue Gene/Q

“…We predict a factor of 400 to 500 throughput improvement over the state of the art, based on other study results [20,26,27], projected to our planned simulations. Through use of low-level communication protocols, we attain near-perfect weak scaling.…”

“…We were able to identify three such efforts, all being published or presented in 2011 [20,26,27]. All three invoke the monodomain approximation and use a reaction-diffusion model based on either reference [29] or [31].…”

Application of an Inverse-Forward Approach to Derive the 12-lead ECG from Body Surface Potential Maps

“…Transmembrane ionic currents were computed with the TNNP model of the human ventricular myocyte [8]. Simulations were performed using the propag-5 software [9] on a Blue Gene/Q supercomputer. Cardiac sequences simulated included 6 paced activation, and 15 re-entrant VTs.…”

Epicardial Fibrosis Explains Increased Transmural Conduction in a Computer Model of Atrial Fibrillation

“…Simulations were performed with the propag-5 software and run on 2560 cores of a Cray XE6 supercomputer [10,11]. Electrical activity was simulated with a mono-domain reaction-diffusion equation.…”