Hybrid Photoacoustic/Ultrasound Tomograph for Real-Time Finger Imaging

Oeri, Milan; Bost, Wolfgang; Senegond, Nicolas; Tretbar, Steffen; Fournelle, Marc

doi:10.1016/j.ultrasmedbio.2017.05.015

Cited by 24 publications

(23 citation statements)

References 22 publications

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“…Efficient integration between MSOT and US in a hybrid hand-held scanner is expected to further accelerate clinical translation of MSOT and significantly enhance imaging performance of the stand-alone systems by simultaneously delivering their highly complementary contrasts. While a number of possible hybridization approaches have been previously suggested [14] , [15] , [16] , [17] , [18] , such an efficient combination is inherently challenged by the fundamentally different excitation and image formation strategies behind the two modalities. Recently, a hand-held probe based on a multi-segment detector array combining linear and concave segments with different inter-element pitch has been reported [19] , [20] .…”

Section: Introductionmentioning

confidence: 99%

Imaging of blood flow and oxygen state with a multi-segment optoacoustic ultrasound array

2018

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Changes in hemodynamic parameters are directly linked to biological function and physiological activity. Characterization of hemodynamics is commonly performed by Doppler ultrasound, which provides accurate measurements of blood flow velocity. Multi-spectral optoacoustic tomography is rapidly undergoing clinical translation fostered by its unique and complementary capacity for label-free mapping of the blood volume and the distribution of oxy- and deoxy-hemoglobin in blood. Here we report on a hybrid optoacoustic and ultrasound imaging approach that enables multi-modal imaging of blood flow and oxygen state using a multi-segment detector array. We further demonstrate rendering of multi-modal pulse-echo ultrasound, multi-spectral optoacoustic tomography, and color Doppler images from carotid artery of a healthy subject.

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Section: Introductionmentioning

confidence: 99%

Imaging of blood flow and oxygen state with a multi-segment optoacoustic ultrasound array

2018

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“…Since PA wavefronts propagate almost isotropically from the signal sources, wide-angle concave array has the optimal arrangement of the transducer elements for fully utilizing their receiving directivity resulting in high SNR. In this section, we summarize clinical PA imaging platforms that use concave and convex array transducers for various clinical studies, e.g., thyroid [47,64], breast [48], peripheral vasculature [29,49,50], prostate [38] and uterine studies [65]. Curved linear array transducers are used in the studies based on Multi-Spectral Optoacoustic Tomography (MSOT) platforms [29,47,48,64].…”

Section: Clinical Pai Systems Based On Curved Linear Array Transducersmentioning

confidence: 99%

“…Concave array transducers are also used in tomographic scanners for imaging human extremities [49,50].…”

Section: Clinical Pai Systems Based On Curved Linear Array Transducersmentioning

confidence: 99%

“…Due to the inherent similarities with the existing US system, some commercially available US systems allow the user to modify the system for laser integration, PA beamforming and display to transform it into a clinical PAI system [45,46]. Customized multi-channel data acquisition systems are used for acquiring PA signals from multiple transducers [29,[47][48][49]. In some applications that require a large tomographic view, motorized stages are used to control the position of PAI transducers synchronized with the data acquisition sequence [30,[49][50][51].…”

Section: Introductionmentioning

confidence: 99%

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Clinical photoacoustic imaging platforms

et al. 2018

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Photoacoustic imaging (PAI) is a new promising medical imaging technology available for diagnosing and assessing various pathologies. PAI complements existing imaging modalities by providing information not currently available for diagnosing, e.g., oxygenation level of the underlying tissue. Currently, researchers are translating PAI from benchside to bedside to make unique clinical advantages of PAI available for patient care. The requirements for a successful clinical PAI system are; deeper imaging depth, wider field of view, and faster scan time than the laboratory-level PAI systems. Currently, many research groups and companies are developing novel technologies for data acquisition/signal processing systems, detector geometry, and an acoustic sensor. In this review, we summarize state-of-the-art clinical PAI systems with three types of the imaging transducers: linear array transducer, curved linear array transducer, and volumetric array transducer. We will also discuss the limitations of the current PAI systems and describe latest techniques being developed to address these for further enhancing the image quality of PAI for successful clinical translation.

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“…This preliminary approach demonstrates i) the value of high-resolution ultrasound scans for the assessment of limb bones and joints, ii) the advantage of un- derwater sonography for gaining artifactreduced images, and iii) the option of advanced 3 D ultrasound image processing at a resolution comparable to magnetic resonance-based methods. First technical reports demonstrate feasible concepts of the clinical implementation of this idea [5]. In this regard, we want to emphasize the need for further technical development towards point-of-care ultrasound-tomography scanners, which may be useful for fast, standardized and efficient assessment of limbs, especially in younger children.…”

Section: Dear Editorsmentioning

confidence: 99%