Hybrid Semiconducting Polymer Dot–Quantum Dot with Narrow-Band Emission, Near-Infrared Fluorescence, and High Brightness

Chan, Yang-Hsiang; Ye, Fangmao; Gallina, Maria Elena; Zhang, Xuanjun; Jin, Yuhui; Wu, I‐Chin; Chiu, Daniel T.

doi:10.1021/ja3022973

Cited by 117 publications

(99 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Semiconducting polymer quantum dots (Pdots) have emerged as a new class of promising fluorescent nanomaterials with high emission rates, extraordinary fluorescence brightness, excellent photostability, high quantum yields, large absorption cross-sections. [21][22][23][24][25][26]. Compared with ordinary fluorescent material, the Pdots are prepared easily, low cost, low cytotoxicity, lack of heavy metal ions.…”

Section: Introductionmentioning

confidence: 99%

O-Phenylenediamine-Cysteine Nanosphere Having Conjugated Structures: A Highly Selective Fluorescent Probe for Mercury Ion

Duan¹,

Song²,

Sun³

et al. 2016

JAN

View full text Add to dashboard Cite

Abstract.A sensitive fluorescent o-phenylenediamine-cysteine copolymer dots (O-Cys) detection system for Hg 2+ was synthesized by a facile and one step hydrothermal method. As a sensitive fluorescent probe, the O-Cys showed excellent linear relationships with detection limit as low as 1.0×10 -11 M with the concentrations of Hg 2+ increasing from 2×10 -11 M to 9×10 -11 M . What's more, the O-Cys for the detection of Hg 2+ was superior to most current methods and fluorescent material. At the same time, the working mechanism of O-Cys for Hg 2+ detection was also explored. Hg 2+ had higher fluorescent quenching ability for as-prepared O-Cys because Hg 2+ was interation with amino group (-NH 2 ) and thiol group (-SH) via a series of contrast test. And -SH enhanced the ability of Hg 2+ detection to some extent. Therefore, this paper provided a good exponent of detection Hg 2+ with low detection limit.

show abstract

Section: Introductionmentioning

confidence: 99%

O-Phenylenediamine-Cysteine Nanosphere Having Conjugated Structures: A Highly Selective Fluorescent Probe for Mercury Ion

Duan¹,

Song²,

Sun³

et al. 2016

JAN

View full text Add to dashboard Cite

show abstract

“…The currently available CP based far‐red (FR)/NIR fluorescent NPs are mainly synthesized through chemical incorporation of narrow‐band‐gap moieties into CP backbones or physical blending of CP and FR/NIR fluorescent acceptors (e.g., organic dyes, quantum dots (QDs), and CPs). [[qv: 27c,d]],28 In these cases, the polymer absorption is strongly dependent on the donor component and the short wavelength is not suitable for in vivo bioimaging. Very recently, we have successfully shifted the absorption maxima of highly emissive FR/NIR fluorescent CP NPs to ≈488 and ≈530 nm, by simultaneous incorporation of two narrow‐band‐gap moieties into CP backbone to realize efficient intra‐ and intermolecular energy transfer 29…”

Section: Introductionmentioning

confidence: 99%

Far‐Red/Near‐Infrared Conjugated Polymer Nanoparticles for Long‐Term In Situ Monitoring of Liver Tumor Growth

Liu

2015

Advanced Science

View full text Add to dashboard Cite

The design and synthesis is reported for a fluorescent conjugated polymer (CP), poly{[4,4,9,9‐tetrakis(4‐(octyloxy)phenyl‐4,9‐dihydro‐s‐indaceno[1,2‐b:5,6‐b′]dithiophene)]‐alt‐co‐[4,7‐di(thiophen‐2‐yl)‐2,1,3‐benzothiadiazole]} (PIDT‐DBT), with absorption and emission profiles fallen within far‐red/near infrared (FR/NIR) region and further demonstrate its application in long‐term in vitro cell tracing and in vivo imaging of liver tumor growth. PIDT‐DBT‐Tat nanoparticles (NPs) have an absorption maximum at ≈600 nm with an emission maximum at ≈720 nm in water. In vitro cell tracing studies reveal that PIDT‐DBT‐Tat NPs can trace HepG2 liver cancer cells over 8 d. In vivo imaging results indicate that PIDT‐DBT‐Tat NPs can monitor liver tumor growth for more than 27 d in a real‐time manner. Both in vitro and in vivo studies demonstrate that PIDT‐DBT‐Tat NPs are superior to commercial Qtracker 705 as fluorescent probes. This study demonstrates for the first time the feasibility for long‐term in vivo imaging of tumor growth by utilizing CP‐based fluorescent probes, which will encourage the development of NIR fluorescent CPs for in vivo bioimaging.

show abstract

“…[10][11][12][13][14][15] As known, in order to intensively realize the nucleus modification and diagnostic, prognostic information, fluorescence cell imaging has matured into a novel platform in recent years. [16][17][18][19][20][21][22] For example, Misra and co-workers prepared some highly photoluminescent semiconductor quantum dots based on ZnO that could be immobilized of HeLa cells, which was beneficial for detecting the cancer cells in cell therapy. [23][24][25] However, the appropriate fluorescent biomaterials that can enter and deposit into the special cellular position are still limited, considering the photostability, cytotoxicity and permeability, which encourages us to prepare microstructures/nanostructures with tuning size and shape based on organic conjugated molecules.…”

Section: Introductionmentioning

confidence: 99%

Self-assembled multicolor nanoparticles based on functionalized twistacene dendrimer for cell fluorescent imaging

Zhang

Liu

et al. 2015

NPG Asia Mater

View full text Add to dashboard Cite

A series of twistacene-functionalized dendrimers were successfully synthesized and characterized. The model molecule DBPy has a twisted configuration with a torsional angle of 27.69°between pyrene and naphthalene units. The resulting compounds TPPh, TTPy, OTPy and TOPhP can self-assemble into organic nanoparticles through re-precipitation method and emit strong blue, cyan, green and red fluorescence in water, respectively. Additionally, the obtained multicolor nanoparticles showed low cytotoxicity and good photostability that selectively flow into the membrane and cytoplasm of HeLa cells, indicating the feasibility and efficiency in fluorescence imaging. This study might be a new avenue for the design of three-dimensional branched conjugated molecule and specific location imaging in living cell.

show abstract

Hybrid Semiconducting Polymer Dot–Quantum Dot with Narrow-Band Emission, Near-Infrared Fluorescence, and High Brightness

Cited by 117 publications

References 28 publications

O-Phenylenediamine-Cysteine Nanosphere Having Conjugated Structures: A Highly Selective Fluorescent Probe for Mercury Ion

O-Phenylenediamine-Cysteine Nanosphere Having Conjugated Structures: A Highly Selective Fluorescent Probe for Mercury Ion

Far‐Red/Near‐Infrared Conjugated Polymer Nanoparticles for Long‐Term In Situ Monitoring of Liver Tumor Growth

Self-assembled multicolor nanoparticles based on functionalized twistacene dendrimer for cell fluorescent imaging

Contact Info

Product

Resources

About