Intelligent mobile robots need to deal with different kinds of uncertainties in order to perform their tasks, such as tracking predefined paths and avoiding static and dynamic obstacles until reaching their destination. In this research, a Robotino® from Festo Company was used to reach a predefined target in different scenarios, autonomously, in a static and dynamic environment. A Type-2 fuzzy logic controller was used to guide and help Robotino® reach its predefined destination safely. The Robotino® collects data from the environment. The rules of the Type-2 fuzzy logic controller were built from human experience. They controlled the Robotino® movement, guiding it toward its goal by controlling its linear and angular velocities, preventing it from colliding obstacles at the same time, as well. The Takagi–Sugeno–Kang (TSK) algorithm was implemented. Real-time and simulation experimental results showed the capability and effectiveness of the proposed controller, especially in dealing with uncertainty problems.