The article presents a multiband symmetrically placed two elements, inverted-F multiple inputs multiple outputs (MIMO) antenna for wireless LAN (WLAN), Industrial, Society and Medical (ISM) band, S-/C-band applications. Decoupling (S 12 < −15 dB) between the two antenna elements of MIMO antenna is improved by introducing metallic vias at the top ends of the patch. The MIMO antenna has been fabricated and measured on a piece of low-cost, low-profile, FR-4 substrate. A combination of parasitic loading of 4-units (quadruplet) of square-split ring resonators (SRRs) and complementary split ring resonator (CSRR) cells have been used to achieve quad-bands for lower than −10 dB total active reflection coefficients and additionally to improve the isolation between antenna elements. The paper also presents the tabularized and graphical investigations of the analyzed and measured resultant MIMO parameters like envelope correlation coefficient (ECC), diversity gain (DG), total active reflection coefficients (TARC), MIMO-VSWR (voltage standing wave ratio), channel capacity loss (CCL), etc. and are found approximately close to each other with small acceptable errors. The other important parameters (reflection coefficients, radiation pattern, E-plane and H-plane polar plots, electric field vector (E) distribution, and current density vector (J) distribution) of the proposed antenna were also demonstrated and measured using a vector network analyzer (Agilent N5247A VNA) and 18 GHz anechoic chamber in the microwave research laboratory. The MIMO (1 × 2) antenna is best suitable for Bluetooth/WLAN/Wi-Fi (2.45-2.57 GHz) and ISM band, FIXED, MOBILE, RADIO Location, Amateur & Amateur-satellite service (2.45 GHz) within impedance bandwidth (S 11 < −10 dB) from 2.45-2.57 GHz lower band, midband at 4.4 GHz, and n46 (5.40-5.49 GHz) upper band.