Hydatid Disease of the Cervical Spine

Ferris, B D; Scott, J. E. S.; Uttley, David

doi:10.1097/00003086-198606000-00031

Cited by 7 publications

(2 citation statements)

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“…Myelography still has a place in postoperative cases. Tuberculotic, metastatic, and other osteolytic bone states are among the differential diagnosis [6]. The most specific antigen is antigen 5 (ARC5) [14].…”

Section: Discussionmentioning

confidence: 99%

Vertebral hydatid cyst infection (Echinococcus granulosus): a case report

Normelli

Aaro²,

Follin³

1998

European Spine Journal

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Section: Discussionmentioning

confidence: 99%

Vertebral hydatid cyst infection (Echinococcus granulosus): a case report

Normelli

Aaro²,

Follin³

1998

European Spine Journal

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“…Damage to the CNS is uncommon and due to cyst formation within the brain, cerebellum, skull or vertebrae and more rarely in brain stem (78,86) or spinal cord (13,20) through vertebral or rib infection.…”

Section: Clinical Manifestationsmentioning

confidence: 99%

Echinococcosis

Taratuto¹,

Venturiello

1997

Brain Pathology

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Echinococcosis is a human disease caused by the larval form of Taenia echinococcus, which lives in the gut of the dog, wild canides and other carnivorous animals which represent the definitive hosts and involves as intermediate hosts both domestic and wild animals. Humans become accidental intermediate hosts by ingesting Taenia eggs. The main species pathogenic for man are E granulosus causing cystic echinococcosis with worldwide distribution and endemic in sheep and cattle breeding countries, and E multilocularis causing alveolar echinococcosis, with preferential distribution in the northern hemisphere. After ingestion of contaminated food, hexacanth embryos migrate by the portal system to liver and later lung, brain and other tissues. Symptoms are related to both cyst location and size. E granulosus infection of the central nervous system (CNS) may be primary or secondary and has been estimated to be low (2%). Sharply demarcated, spherical and intraparenchymal, cysts may reach a large size causing neurological symptoms. Spilling of cyst fluid due to trauma or surgery may trigger anaphylaxis as well as disseminated infection. Host reaction is minimal in the brain but a foreign giant cell reaction may develop. E multilocularis develops within the liver as a rapid invasive pseudomalignant growth and may metastasize to the CNS, where estimated incidence reaches 5%. Hydatid antigens induce an immune reaction in the host which is helpful for the diagnosis. DNA probes and PCR may be applied to differentiate between Echinococcus spp. Although the host develops an immunological protection from reinfection, the parasite evades host immune attack. A wide range of evasion mechanisms have been advanced, including a barrier for host cells due to hydatid cyst laminated cuticle, polyclonal activation of lymphocytes by parasite soluble antigens, and depression of host cell immune responses. Chronic stimulation of the host by cyst fluid antigens leads to increased specific IgG4 production, which might act as blocking antibodies against anaphlaxis suggestive of host response immunomodulation.

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Hydatid Cyst of Bone: Diagnosis and Treatment

et al. 2001

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Osseous hydatidosis is a rare occurrence of hydatid disease. Anatomoclinical changes are, however, peculiar to this localization. From the anatomopathologic standpoint, this localization marks the torpid, insidious progression of the parasite into bone tissue, leading to an immediate diffuse, extensive, invasion process, so complete surgical eradication is rarely possible. From the clinical standpoint, whatever the localization may be, we are surprised by the latency of this affection, the patient being treated at an advanced stage, when radiologic lesions are already extensive, and the complications, especially in the spinal area, are severe. Owing to the poor biologic findings, the diagnosis of osseous hydatidosis is still primarily based on roentgenographic findings. Sometimes, however, the diagnosis is established only after surgery. Treatment of osseous hydatidosis is closer to oncologic therapy than to the usual surgical treatment of visceral hydatid cysts. Because of the poor results with medical treatment, osseous hydatidosis must be treated by a radical operation with wide excision, adapted to each localization. In the main, the prognosis of osseous hydatidosis remains poor, especially with spinal and pelvic localizations, which are the most frequent ones. The prognosis and treatment of osseous hydatidosis belong in the same category as a locally malignant lesion.

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Hydatid Disease of the Cervical Spine

Cited by 7 publications

References 0 publications

Vertebral hydatid cyst infection (Echinococcus granulosus): a case report

Vertebral hydatid cyst infection (Echinococcus granulosus): a case report

Echinococcosis

Hydatid Cyst of Bone: Diagnosis and Treatment

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