Hydration of monosaccharides studied by Raman scattering

Abstract

We report a Raman spectroscopy study of glucose, fructose, and mannose. The spectra have been recorded for the dry powders and for solutions in H2O and D2O and commented in the so‐called “fingerprint region” of the spectra (200–1,400 cm−1), in order to study the influence of the interaction with water on the solute vibrational modes. We have evidenced splitting of some bands, due to the presence of different anomers in solution. The isotopic substitution of the solvent has allowed in some instances to confirm the band assignment and, in other cases, to propose new assignments. Importantly, the isotopic substitution of the solvent has evidenced differences in the interaction of the investigated monosaccharides with water, which are rationalized as due to a balance between the inertia of the oscillator due to H‐bonding and bond strength. In particular, glucose and fructose interact strongly with water, whereas in the case of mannose, we have observed a weaker interaction with water and a different behaviour of its anomers.

Measurement of cartilage sub‐component distributions through the surface by Raman spectroscopy‐based multivariate analysis

“…Figure 5A shows an overlay of the reference OCA spectra and cartilage at a depth of 100 μm. Dominant OCA peaks are present at 1003 cm −1 from symmetric CcN stretching in urea, [ 23 ] 628 cm −1 from D‐(−)‐fructose CCO 5 groups, and 524 cm −1 from the pyranose ring in D‐(−)‐fructose [ 24 ] among others. Figure 5B shows the postclear stage MCR deconvolutions, illustrating where OCA peaks coincide with other sub‐components.…”

Recent advances in linear and nonlinear Raman spectroscopy. Part XIII

“…Ruggiero et al used Raman to study the hydration of the monosaccharides glucose, fructose, and mannose. They found that glucose and fructose interact strongly with water, whereas for mannose, a weaker interaction with water and a different behaviour of its anomers, was observed . Xu and co‐workers used Raman and quantum chemistry calculations to probe the structural organization of N ‐methyl‐2‐pyrrolidinone in binary mixtures .…”

“…They found that glucose and fructose interact strongly with water, whereas for mannose, a weaker interaction with water and a different behaviour of its anomers, was observed. [181] Xu and co-workers used Raman and quantum chemistry calculations to probe the structural organization of N-methyl-2-pyrrolidinone in binary mixtures. [182] Zhu and co-workers performed Raman measurements and ab initio quantum chemical calculations of ion association behaviour in calcium nitrate solution.…”

GISR 2017: Present and future of Raman researches in Italy

“…The Raman spectroscopy study of hydration of a series of monosaccharide such as glucose, fructose, and mannose pointed out the contribution provided by this spectroscopy technique for probing the hydration shell structure in these systems. The analysis of Raman spectra recorded for the dry powders and for solutions of monosaccharides in H 2 O and D 2 O revealed the presence of a characteristic “fingerprint region” where the spectral changes of some vibrational bands were interpreted as signature of the influence of the interaction with water.…”