Hydrazones as analytical reagents: a review

Singh, Rahul; Jain, P. K.; Singh, Rishi Pal

doi:10.1016/0039-9140(82)80024-6

Cited by 149 publications

(84 citation statements)

References 89 publications

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“…Therefore, a number of hydrazone derivatives have been claimed to possess interesting anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, antimalarial, antimicrobial, antitumoral and antiviral activities [12][13][14][15][16][17][18][19]. Furthermore, hydrazones can display antitubercular effects based on their tendency to form stable metal chelates with transition metal ions [20], which catalyze the physiological processes [21].…”

Section: Introductionmentioning

confidence: 99%

DETERMINATION OF THE DISSOCIATION CONSTANTS OF SOME p-SUBSTITUTED AROMATIC HYDRAZONES

Jankulovska¹,

Spirevska²,

Ragjenovikj³

2017

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A b s t r a c t: The acid-base behavior of five p-substituted aromatic hydrazones has been studied, using UV spectrophotometric method. The influence of the acidity of the medium on the absorption spectra is followed in aqueous sodium hydroxide solutions in pH region from 7 to 14. The measurements are performed at room temperature, and at ionic strength of 0.1, 0.25 and 0.5 mol dm -3 . A batochromic shift of the absorption band that appears in neutral media is observed, when pH is up to 7. It suggests that the dissociation process of the amide and hydroxyl group takes place. Deprotonation enthalpies and total energy values are calculated by using the semiempirical methods AM1 and PM3. Using the changes in the UV spectra with pH of the solution, the determination of dissociation constants, pK BH , at three different ionic strengths, as well as, the thermodynamic dissociation constants at zero ionic strength, is performed. In order to obtain more precise results, the calculations are made from the absorbance values at four selected wavelengths. Furthermore, the pK BH values were determined graphically from the intercept of the dependence of logI on pH. The results showed that the numerically calculated pK BH values are identical to those graphically obtained.

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Section: Introductionmentioning

confidence: 99%

DETERMINATION OF THE DISSOCIATION CONSTANTS OF SOME p-SUBSTITUTED AROMATIC HYDRAZONES

Jankulovska¹,

Spirevska²,

Ragjenovikj³

2017

Contributions

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“…The reasons are manifold: the versatile biological activities, such as antibacterial and antitubercular, [4][5][6] the coordination abilities to most metal ions, 7,8 and promising properties for analytical applications. 9,10 As is well known that properties of any material are based on their structures, so, in recent years, the crystal structures of benzohydrazone compounds have attracted much attention. 1,11,12 Recently, Zhang and co-workers have reported the structures and antimicrobial activity of a series of halo-substituted aroylhydrazones.…”

Section: Introductionmentioning

confidence: 99%

Crystal Structures and Antimicrobial Activities of N'-[2,5-Dihydroxybenzylidene]-3,4,5-Trimethoxybenzohydrazide, N'-[2,4-Dichlorobenzylidene]-3,4,5-Trimethoxybenzohydrazide, and 2,4-Dichloro-N'-(2-Hydroxy-3-Methoxy-5-Nitrobenzylidene)benzohydrazide Ethanol Solvate

Han

2013

J. Chil. Chem. Soc.

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“…onde R, R', X e Y podem ser iguais a H, alcanos, RCO, grupos heterocíclicos. O nome geral "hidrazonas" é usado para todos os compostos que apresentam a estrutura geral (I) (7).…”

Section: -Alguns Aspectos Sobreunclassified

“…Por exemplo, o composto sintetizado a partir da reação de benzaldeído com fenilhidrazina é denominado benzaldeído fenilhidrazona (7). O ligante, objeto deste trabalho, sintetizado a partir da di-2-piridil cetona e da benzoilhidrazina é denominado di-2-piridil cetona benzoilhidrazona.…”

Section: I2 -Nomenclaturaunclassified

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Determinação das constantes de dissociação/ionização da di-2-piridil cetona benzoilhidrazona (DPKBH) em diferentes porcentagens de etanol

Gaubeur¹

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ions in the presence of organic species found in natural waters.So as to better understand the DPKBH properties In ethanol, it was necessary to determine the dissociation/ionization constant in different percentages of ethanol (lO, 19, 29 and 48%). In these ethanol percentages, through absolute pH measurements, pKs of DPKBH could be the found by using the potentiometric technique, and in 10 and 48% of ethanol the pKs of DPKBH were determined with pH measurements associated to absorbance of the species present in the equilibria by using the spectrophotometric technique.In appropiate percentage of ethanol the behavior of the glass electrode was previously determined.

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Hydrazones as analytical reagents: a review

Cited by 149 publications

References 89 publications

DETERMINATION OF THE DISSOCIATION CONSTANTS OF SOME p-SUBSTITUTED AROMATIC HYDRAZONES

DETERMINATION OF THE DISSOCIATION CONSTANTS OF SOME p-SUBSTITUTED AROMATIC HYDRAZONES

Crystal Structures and Antimicrobial Activities of N'-[2,5-Dihydroxybenzylidene]-3,4,5-Trimethoxybenzohydrazide, N'-[2,4-Dichlorobenzylidene]-3,4,5-Trimethoxybenzohydrazide, and 2,4-Dichloro-N'-(2-Hydroxy-3-Methoxy-5-Nitrobenzylidene)benzohydrazide Ethanol Solvate

Determinação das constantes de dissociação/ionização da di-2-piridil cetona benzoilhidrazona (DPKBH) em diferentes porcentagens de etanol

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