Hydrocephalus in children born in 1999–2002: epidemiology, outcome and ophthalmological findings

Persson, Eva; Anderson, Susann; Wiklund, Lars‐Martin; Uvebrant, Paul

doi:10.1007/s00381-007-0324-7

Cited by 80 publications

(64 citation statements)

References 50 publications

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“…The prevalence of infantile hydrocephalus is 0.48, and that for hydrocephalus associated with spina bifida is 0.18 (Persson, Anderson, Wiklund, & Uvebrant, 2007). The incidence of spina bifida in low-income countries is higher: 2.61/1000 live births in Tanzania (Kinasha & Manji, 2002), and 7/1000 deliveries in Nigeria (Airede, 1992).…”

Section: Spina Bifida and Hydrocephalusmentioning

confidence: 95%

Community Knowledge, Beliefs, Attitudes, and Practices towards Children with Spina Bifida and Hydrocephalus in Uganda

Bannink

Stroeken

Idro

et al. 2015

International Journal of Disability, Development and Education

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This article describes the findings of a qualitative study on knowledge, beliefs, attitudes, and practices towards children with spina bifida and hydrocephalus in four regions of Uganda. Focus group discussions and semi-structured interviews were held with parents of children with spina bifida and hydrocephalus, policy-makers, and service providers. Our findings describe how negative knowledge, beliefs, attitudes, and practices create barriers to treatment and inclusion of children with spina bifida and hydrocephalus and their parents in Uganda. The findings show how knowledge, beliefs, attitudes, and practices evolve over time, are both similar and differ in the various regions, and become more conducive towards accessing treatment and achieving inclusion. Sensitisation and early intervention including parents and service providers in dissemination of knowledge, rehabilitative care to set the trend for positive change and support, as well as longitudinal studies of children with spina bifida and hydrocephalus and their parents are recommended.

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Section: Spina Bifida and Hydrocephalusmentioning

confidence: 95%

Community Knowledge, Beliefs, Attitudes, and Practices towards Children with Spina Bifida and Hydrocephalus in Uganda

Bannink

Stroeken

Idro

et al. 2015

International Journal of Disability, Development and Education

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“…20 In 2005, Tisell et al 25 estimated the incidence of adult-onset hydrocephalus requiring surgery to be 3.4 per year per 100,000 population in Sweden. With recent advances and availability of diagnostic tools, an increasing number of cases are being diagnosed early in the disease 12,16 Similarly, the ease of diagnosis with simple diagnostic procedures such as CT scanning has increased the detection of hydrocephalus from different pathologies.…”

Section: Incidence and Prevalencementioning

confidence: 99%

Epidemiology of adult-onset hydrocephalus: institutional experience with 2001 patients

Bir

Patra

Maiti

et al. 2016

FOC

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OBJECTIVE Adult-onset hydrocephalus is not commonly discussed in the literature, especially regarding its demographic distribution. In contrast to pediatric hydrocephalus, which is related to a primary CSF pathway defect, its development in adults is often secondary to other pathologies. In this study, the authors investigated the epidemiology of adult-onset hydrocephalus as it pertains to different etiologies and in reference to age, sex, and race distributions. METHODS The authors retrospectively reviewed the clinical notes of 2001 patients with adult-onset hydrocephalus who presented to Louisiana State University Health Sciences Center within a 25-year span. Significant differences between the groups were analyzed by a chi-square test; p < 0.05 was considered significant. RESULTS The overall mean (± SEM) incidence of adult hydrocephalus in this population was 77 ± 30 per year, with a significant increase in incidence in the past decade (55 ± 3 [1990–2003] vs 102 ± 6 [2004–2015]; p < 0.0001). Hydrocephalus in a majority of the patients had a vascular etiology (45.5%) or was a result of a tumor (30.2%). The incidence of hydrocephalus in different age groups varied according to various pathologies. The incidence was significantly higher in males with normal-pressure hydrocephalus (p = 0.03) or head injury (p = 0.01) and higher in females with pseudotumor cerebri (p < 0.0001). In addition, the overall incidence of hydrocephalus was significantly higher in Caucasian patients (p = 0.0002) than in those of any other race. CONCLUSIONS Knowledge of the demographic variations in adult-onset hydrocephalus is helpful in achieving better risk stratification and better managing the disease in patients. For general applicability, these results should be validated in a large-scale meta-analysis based on a national population database.

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“…Cerebrospinal Fluid (CSF) is produced by secretory cells of the choroid plexus at a rate of approximately 20 ml per hour, circulates through the ventricular system and is finally absorbed into the venous system via the superior sagittal sinus. The occurrence of hydrocephalus in newborn children is about 1 out of 500-2,000 (Murshid et al 2000;Persson et al 2007).…”

Section: Introductionmentioning

confidence: 99%

Development and in-vitro characterization of an implantable flow sensing transducer for hydrocephalus

Bork¹,

Hogg²,

Lempen

et al. 2010

Biomed Microdevices

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An implantable transducer for monitoring the flow of Cerebrospinal fluid (CSF) for the treatment of hydrocephalus has been developed which is based on measuring the heat dissipation of a local thermal source. The transducer uses passive telemetry at 13.56 MHz for power supply and read out of the measured flow rate. The in vitro performance of the transducer has been characterized using artificial Cerebrospinal Fluid (CSF) with increased protein concentration and artificial CSF with 10% fresh blood. After fresh blood was added to the artificial CSF a reduction of flow rate has been observed in case that the sensitive surface of the flow sensor is close to the sedimented erythrocytes. An increase of flow rate has been observed in case that the sensitive surface is in contact with the remaining plasma/artificial CSF mix above the sediment which can be explained by an asymmetric flow profile caused by the sedimentation of erythrocytes having increased viscosity compared to artificial CSF. After removal of blood from artificial CSF, no drift could be observed in the transducer measurement which could be associated to a deposition of proteins at the sensitive surface walls of the packaged flow transducer. The flow sensor specification requirement of +-10% for a flow range between 2 ml/h and 40 ml/h. could be confirmed at test conditions of 37 degrees C.

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Hydrocephalus in children born in 1999–2002: epidemiology, outcome and ophthalmological findings

Cited by 80 publications

References 50 publications

Community Knowledge, Beliefs, Attitudes, and Practices towards Children with Spina Bifida and Hydrocephalus in Uganda

Community Knowledge, Beliefs, Attitudes, and Practices towards Children with Spina Bifida and Hydrocephalus in Uganda

Epidemiology of adult-onset hydrocephalus: institutional experience with 2001 patients

Development and in-vitro characterization of an implantable flow sensing transducer for hydrocephalus

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