Located on the Atlantic coast, the city of Pointe-Noire is the economic capital of the Republic of Congo. It enjoys strong industrial activity, particularly oil, with the presence of a refinery and onshore drilling in its surroundings. The steady growth of its population leads to an increase in its drinking water supply needs, produced mainly from the exploitation of its aquifer system. Thus, in view of the growth of its human activities, the interest of permanent monitoring of the quality of its groundwater is becoming more and more great. The present study aims to assess the physicochemical quality of the groundwater in the AQ2 aquifer of the Pointe-Noire region during the period from 2017 to 2020, and to understand the processes that are at the origin of the mineralization of these waters. To this end, we obtained from the water supply company, La Congolaise Des Eaux (LCDE) seventy-five (75) water analysis reports bulletins representing the average values of thirteen (13) physicochemical parameters in each of the 75 boreholes used for this study so as to homogeneously cover the entire city. The Piper diagram revealed that the waters are dominated by three types of facies: K-Na-Cl, Mg-Ca-SO 4 -Cl and Mg-Ca-HCO 3 . The presence of the K-Na-Cl facies is due to the high levels of chlorides and sodium in the water-rock. The Principal Component Analysis (PCA) indicates that the mineralization of these waters results in the hydrolysis of silicate minerals. The Ascending Hierarchical Classification (AHC) analysis made it possible to determine the parameters that categorize the different classes from 2017 to 2020, these are TDS, EC and TH and to a lesser extent Ca 2+ , Mg 2+ , HCO 3 and TAC. Overall, the quality of the groundwater is good according to standards WHO, but in some cases requires specific treatment before supply.