The velocity profiles and separation efficiency curves of a hydrocyclone were predicted by an Euler-Euler approach using a computational fluid dynamics tool ANSYS-CFX 14.5. The Euler-Euler approach is capable of considering the particle-particle interactions and is appropriate for highly laden liquid-solid mixtures. Predicted results were compared and validated with experimental results and showed a considerably good agreement. An increase in the particle cut size with increasing solid concentration of the inlet mixture flow was observed and discussed. In addition to this, the erosion on hydrocyclone walls constructed from stainless steel 410, eroded by sand particles (mainly SiO 2 ), was predicted with the Euler-Lagrange approach. In this approach, the abrasive solid particles were traced in a Lagrangian reference frame as discrete particles. The increases in the input flow velocity, solid concentration, and the particle size have increased the erosion at the upper part of the cylindrical body of the hydrocyclone, where the tangential inlet flow enters the hydrocyclone. The erosion density in the area between the cylindrical to conical body area, in comparison to other parts of the hydrocyclone, also increased considerably. Moreover, it was observed that an increase in the particle shape factor from 0.1 to 1.0 leads to a decrease of almost 70 % in the average erosion density of the hydrocyclone wall surfaces.