“…Since heavy quarks essentially emerge in early, hard processes, they witness the course of heavy-ion collision-either as individual entities or subjects of dissociating and regenerating bound states [3][4][5]. Accordingly, the heavy-quark physics addresses such issues as charm (c,c) and bottom (b,b) dynamics related to transport coefficients [6][7][8][9][10] in the rapidly evolving and highly anisotropic ambient quark-gluon medium [11,12] as well as cc and bb states as open quantum systems [13][14][15][16]. The rich body of experimental data from LHC, and also from RHIC , enabled a tremendous refinement of our understanding of heavy-quark dynamics.…”