Hydrogels and their medical applications

Rosiak, Janusz M.; Yoshii, Fumio

doi:10.1016/s0168-583x(99)00118-4

Cited by 410 publications

(225 citation statements)

References 12 publications

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“…The main areas of hydrogels applications today include [3]: (i) topical applications as wound dressings; (ii) drug delivery systems; (iii) transdermal systems; (iv) dental applications; (v) injectable polymers; (vi) implants; (vii) ophthalmic applications and (viii) stimuli-responsive systems.…”

Section: Introductionmentioning

confidence: 99%

Direct UV photocrosslinking of poly(N-vinyl-2-pyrrolidone) (PVP) to produce hydrogels

Lopergolo

Lugão

Catalani

2003

Polymer

125

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Hydrogels for biomedical purposes, made from synthetic polymers as starting materials and free of co-adjuvant molecules, have been produced almost exclusively by high-energy radiative processes. On the other hand, UV photocrosslinking of such materials has been used in conjunction of monomers and/or photoinitiators. This work was addressed to the analysis of poly(N-vinyl-2-pyrrolidone) (PVP) submitted to direct photocrosslinking in aqueous solution, using low pressure Hg lamp (l em ¼ 254 nm). The process efficiency was evaluated, and the properties of the hydrogel formed were determined. The product thus formed has similar micro-and macroscopic properties, as compared to hydrogels produced by high-energy radiation and presents no cytotoxicity. These results demonstrated the viability of using this method as a versatile alternative to hydrogel production, broadening the possibility of its production where high-energy radiation facilities are not available. q

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Section: Introductionmentioning

confidence: 99%

Direct UV photocrosslinking of poly(N-vinyl-2-pyrrolidone) (PVP) to produce hydrogels

Lopergolo

Lugão

Catalani

2003

Polymer

125

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“…6 Hydrogels have the ability to absorb fluid thousands of times their dry weight. 7 Since these gels are used in all wound types, their rheological profile is such that they stay in place after application to the wound and can remain in situ for relatively long periods of time. 8 …”

Section: Clinical Relevancementioning

confidence: 99%

Clinical and Antibiofilm Efficacy of Antimicrobial Hydrogels

Finnegan

Percival

2015

Advances in Wound Care

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“…25 Resulting PVP complex with Lugol Reagent (PVP-I 3 -) absorbs at 400 nm, and the PVP concentration was obtained using appropriate calibration curve. The encapsulation yield (EY) was calculated using Equation 1. (1) where is the mass of encapsulated PVP in the vesicles pellet and 0.4 is the mass of PVP in the initial solution (in g).…”

Section: Pvp Encapsulation In Liposomementioning

confidence: 99%

Preparation of PVP hydrogel nanoparticles using lecithin vesicles

Bueno¹,

Catalani²,

Perez³

et al. 2010

Quím. Nova

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Recebido em 21/6/10; aceito em 20/8/10; publicado na web em 15/10/10 Hydrogels micro, sub-micro and nanoparticles are of great interest for drug encapsulation and delivery or as embolotherapic agents. In this work it is described the preparation of nano and sub-microparticles of pre-formed, high molecular weight and monomer free poly(N-vinyl-2-pyrrolidone) encapsulated inside the core of lecithin vesicles. The hydrogel particles are formed with a very narrow diameter distribution, of about 800 nm, and a moderate swelling ratio, of approximately 10.

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Hydrogels and their medical applications

Cited by 410 publications

References 12 publications

Direct UV photocrosslinking of poly(N-vinyl-2-pyrrolidone) (PVP) to produce hydrogels

Direct UV photocrosslinking of poly(N-vinyl-2-pyrrolidone) (PVP) to produce hydrogels

Clinical and Antibiofilm Efficacy of Antimicrobial Hydrogels

Preparation of PVP hydrogel nanoparticles using lecithin vesicles

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