“…The literature survey supports the fact that Pectin has controlled release attributes as well as gelation capability which is attributed to the degree of esterification. Moreover, Pectin depicts pH-responsive behavior which aids in colon targeting ( Gupta et al, 2002 , Liu et al, 2007 , Sundar Raj et al, 2012 , Grande and Rohman, 2019 , Naik et al, 2020 ). Natrosol (hydroxyethyl cellulose) (HEC) is a synthetic polymer; a polysaccharide derivative having thickening, gelling, stabilizing, and water-retaining properties ( El Fawal et al, 2018 ).…”