Chem. Sci.
 2024
DOI: 10.1039/d4sc06108j
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Hydrogen-bonding behavior of amidines in helical structure

Emily A. O'Brien,
Jeffrey A. Purslow,
Brendan J. Wall
et al.

Abstract: Amidines are an isostere of the amide bond and are completely unexplored in peptide secondary structure. This study marks the first investigation of the structural implications of amidines in folded...

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