Hydrogen Breath Tests in Gastrointestinal Diseases

Rana, Satya Vati; Malik, Aastha

doi:10.1007/s12291-014-0426-4

Cited by 68 publications

(56 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The most frequently used cut‐off value for test positivity is 10–12 ppm . In the previous studies from our center as well in recent reviews, a cut‐off value of 10 ppm from baseline has been used to indicate a positive breath test.…”

Section: Discussionmentioning

confidence: 99%

Risk of small intestinal bacterial overgrowth in patients receiving proton pump inhibitors versus proton pump inhibitors plus prokinetics

et al. 2018

View full text Add to dashboard Cite

Background and AimIntestinal dysmotility is considered a risk factor for small intestinal bacterial overgrowth (SIBO). Prokinetics improve intestinal motility and are often prescribed with proton pump inhibitors (PPIs) in patients with gastroesophageal reflux disease (GERD) and/or functional dyspepsia. The present study aimed to evaluate the prevalence of SIBO and the orocecal transit time (OCTT) in patients taking PPI compared with those taking PPI plus prokinetics.MethodsThe study is a single‐center, cross‐sectional study. Enrolled patients (with age > 12 years) were divided into two groups: patients taking PPIs for more than 3 months (Group A) and those taking PPIs with prokinetics for more than 3 months (Group B) for various indications. Lactulose breath test (LBT) for OCTT and glucose breath test (GBT) for SIBO were conducted for all patients.ResultsOf the 147 enrolled patients, SIBO was documented in 13.2% patients in Group A versus 1.8% in Group B, P = 0.018. Median OCTT in Group A was 130 (105–160) min compared with 120 (92.5–147.5) min in Group B (P = 0.010). Median OCTT among SIBO‐positive patients was 160 (140–172.5) min compared with SIBO‐negative patients, where it was 120 (103.75–150) min (P = 0.002). The duration and type of PPI used were not associated with the occurrence of SIBO in our study.ConclusionThe use of prokinetics in patients on PPI may reduce the risk of SIBO by enhancing intestinal motility and may reduce SIBO risk associated with long‐term PPI use.

show abstract

Section: Discussionmentioning

confidence: 99%

Risk of small intestinal bacterial overgrowth in patients receiving proton pump inhibitors versus proton pump inhibitors plus prokinetics

et al. 2018

View full text Add to dashboard Cite

show abstract

“…It is mostly a man-made product that is used as a reagent in chemical industry, as fuel, as a power generator, or as cooler in power plants. It is a marker in human breath related to metabolic diseases (e.g., lactose intolerance or malabsorption) [93][94][95].…”

Section: Target Gasesmentioning

confidence: 99%

Year 2020: A Snapshot of the Last Progress in Flexible Printed Gas Sensors

Fioravanti

Carotta

2020

Applied Sciences

View full text Add to dashboard Cite

A review of recent advances in flexible printed gas sensors is presented. During the last years, flexible electronics has started to offer new opportunities in terms of sensors features and their possible application fields. The advent of this technology has made sensors low-cost, thin, with a large sensing area, lightweight, wearable, flexible, and transparent. Such new characteristics have led to the development of new gas sensor devices. The paper makes some statistical remarks about the research and market of the sensors and makes a shot of the printing technologies, the flexible organic substrates, the functional materials, and the target gases related to the specific application areas. The conclusion is a short notice on perspectives in the field.

show abstract

“…Various gases are produced in our gut due to chemical and enzymatic interactions, and bacterial fermentation. While hydrogen breath tests provide insight into the pathophysiology of small intestinal bacterial overgrowth and carbohydrate malabsorption disorders, gases measured from the mouth are low in concentration and location nonspecific . In addition, gut oxygen levels, like gut pH levels, can be a rough indicator of the location of the capsule within the gut (Figure c).…”

Section: Capsules For Robotic Sensingmentioning

confidence: 99%

Robotics in the Gut

Min

Yang

et al. 2019

Advanced Therapeutics

View full text Add to dashboard Cite

Since the advent of ingestible temperature sensors and capsule endoscopes, rapid advances in electronics, robotics, nanotechnology, and material sciences have opened the door for the development of novel medical ingestible robots. The untethered robots provide direct, non-invasive access to the entire gastrointestinal (GI) tract. Furthermore, the tissues, gases, and fluids of the gastrointestinal lumen contain a multitude of biomarkers indicative of gut diseases and health. Ingestible medical robots equipped with advanced imaging and sensing techniques can enable the diagnosis and monitoring of diseases, while providing a better pathophysiological understanding of gastrointestinal disorders. In addition, various robotic actuation mechanisms in the macro-and microscale can realize enhanced drug delivery and surgical interventions for the treatment of diseases. In this paper, an overview of recent advances in ingestible robots toward imaging, sensing, drug delivery, and surgical applications in the GI tract is provided. Key challenges and strategies for the development of novel ingestible robots and future directions of ingestible robots toward precision medicine are also discussed.

show abstract

Hydrogen Breath Tests in Gastrointestinal Diseases

Cited by 68 publications

References 38 publications

Risk of small intestinal bacterial overgrowth in patients receiving proton pump inhibitors versus proton pump inhibitors plus prokinetics

Risk of small intestinal bacterial overgrowth in patients receiving proton pump inhibitors versus proton pump inhibitors plus prokinetics

Year 2020: A Snapshot of the Last Progress in Flexible Printed Gas Sensors

Robotics in the Gut

Contact Info

Product

Resources

About