Hydrogen Peroxide Detection by Super-Porous Hybrid CuO/Pt NP Platform: Improved Sensitivity and Selectivity

Abstract

A super-porous hybrid platform can offer significantly increased number of reaction sites for the analytes and thus can offer advantages in the biosensor applications. In this work, a significantly improved sensitivity and selectivity of hydrogen peroxide (H2O2) detection is demonstrated by a super-porous hybrid CuO/Pt nanoparticle (NP) platform on Si substrate as the first demonstration. The super-porous hybrid platform is fabricated by a physiochemical approach combining the physical vapor deposition of Pt NPs and electrochemical deposition of super-porous CuO structures by adopting a dynamic hydrogen bubble technique. Under an optimized condition, the hybrid CuO/Pt biosensor demonstrates a very high sensitivity of 2,205 µA/mM∙cm2 and a low limit of detection (LOD) of 140 nM with a wide detection range of H2O2. This is meaningfully improved performance as compared to the previously reported CuO-based H2O2 sensors as well as to the other metal oxide-based H2O2 sensors. The hybrid CuO/Pt platform exhibits an excellent selectivity against other interfering molecules such as glucose, fructose, dopamine, sodium chloride and ascorbic acid. Due to the synergetic effect of highly porous CuO structures and underlying Pt NPs, the CuO/Pt architecture offers extremely abundant active sites for the H2O2 reduction and electron transfer pathways.

High-Performance Non-Enzymatic Electrochemical Dopamine Sensors Based on Metal-Organic Framework Derived Co-C-Matrix Nanoplatforms

“…At low pH, the acidic medium of the amine group in DA is protonated, which is not suitable for sensing activity. 55 In addition, the low redox peaks observed at pH > 7 indicate that the DA act stably at high pH values ranging from 7 to 7.4, which is compatible with the pH level of human blood 56 . Figures 5e and 5f show the relationship between the scan rates and the corresponding currents in PBS.…”

“…6d, for which the linear regression equation was extracted (R 2 = 0.9727). The sensitivity and limit of detection (LOD) of the biosensor were calculated using the following equations: 56 Sensitivity S m A 4…”

g-C3N4 Nanosheet Supported CuO Nanocomposites for the Electrochemical Carbon Dioxide Reduction Reaction

“…Prereduction of Nonthermally Treated Samples. CV of as-syn CuO, Figure 6, shows two reduction peaks at around 0.4 and −0.1 V vs RHE, which are attributed to the Cu(II)/ Cu(I) and Cu(I)/Cu(0) reduction couples, respectively, 60 although the theoretical reduction potentials of both steps are slightly more positive. 5 The convoluted oxidation peak might be due to a mix of Cu(0)/Cu(I) and Cu(I)/Cu(II) oxidation processes.…”

A copper oxide nanorod derived metal–organic framework nanocomposite: a robust and sensitive electrocatalyst for the detection of furazolidone

“…This peak is related to the one-electron reduction of Cu(II) to Cu(I). 40 For the GCE in 0.10 mmol L À1 FUZ, a reduction peak at À0.49 V is observed. This peak is related to the irreversible reduction of the nitro group (-NO 2 ) to nitroso.…”