The uplift and denudation of the Colorado Plateau is important in reconstructing the geomorphic and tectonic evolution of western North America. A Late Cretaceous (64 ± 2 Ma) U‐Pb age for the Long Point limestone on the Coconino Plateau, which overlies a regional erosional surface developed on Permo‐Triassic formations, supports unroofing of the Coconino Plateau part of Grand Canyon by that time. U‐Pb analyses of three separate outcrops of this limestone gave ages of 64.0 ± 0.7, 60.5 ± 4.6, and 66.3 ± 3.9 Ma, which dates are older than a fossil‐based, early Eocene age. Samples of the Long Point limestone were dated using the isotope dilution isochron method on well‐preserved carbonates having high‐uranium and low‐lead concentrations. Our U‐Pb ages on the Long Point limestone place important constraints on the (1) time of tectonic uplift of the southwestern Colorado Plateau and Kaibab arch, (2) time of denudation of the Coconino Plateau, and (3) Late Cretaceous models of paleocanyon incision west of, or across, the Kaibab arch. We propose that the age of the Long Point limestone, interbedded within the Music Mountain Formation in the Long Point area, represents a period of regional aggradation and a time of drainage blockage northward and eastward across the Kaibab arch, with possible diversion of northward drainage on the Coconino Plateau westward around the arch via a Laramide paleo‐Grand Canyon.