Hydrolaparoscopy in the rabbit: A fine model for the development of operative fetoscopy

3D vs. 2D simulated fetoscopy for spina bifida repair: a quantitative motion analysis

“…In an adult male New Zealand rabbit animal model all operative steps and surgical conditions present in current clinical multi-layered fetoscopic spina bifida repair, can be simulated. The rabbit’s abdominal cavity mimics the available intra-uterine workspace (15 10 5 cm) when insufflated with 3 l, of CO at a pressure of 5 mmHg 23 . The back of the fetus (22–24 weeks of gestation) is represented by the rabbit stomach 24 .…”

Techniques of Experimentation

“…For ease in observation, the animal may be placed in a steep Trendelenburg (head down) position for access to abdominal and pelvic anatomy, while reverse Trendelenberg may be used for gastric, diaphragmatic, and hepatic procedures. Laparoscopy of experimental animals as a generalized technique has been used extensively for training of physicians (West et al, 1999;Ravizzini et al, 1999;Olinger et al, 1999;Quintero et al, 1994;Gutt et al, 1998). Perfection of this technique has permitted visualization and color photography of the ovaries, ovarian biopsy, injections into the ovary, aspiration of follicle contents, and artificial insemination (Graham, 1976).…”

Tracheal Gas Insufflation-Aided Mechanical Ventilation during Carbon Dioxide-Induced Pneumoperitoneum in Rabbits

“…65(8): 907-912, 2003 Laparoscopic procedures, including laparoscopic diagnosis, appendectomy, cholecystectomy, liver biopsy, hypertrophic pyloric stenosis, splenectomy, and adhesive intestinal obstruction are being performed increasingly in neonates and children [3,25]. Rabbits have been reported as appropriate training models with which to practice the skills needed for laparoscopic surgery in neonates or infants due to their size and abdominal anatomy [11,19,20].Although laparoscopic procedures appear to be associated with a low operative mortality rate through small incision and reduced operative dissection, the serious hypercapnia and respiratory acidosis may develop during carbon dioxide-induced pneumoperitoneum (CDP) [6,9,24]. The ensuing respiratory acidosis induced by hypercapnia can contribute to arrhythmias and even cardiovascular collapse.…”

“…65(8): 907-912, 2003 Laparoscopic procedures, including laparoscopic diagnosis, appendectomy, cholecystectomy, liver biopsy, hypertrophic pyloric stenosis, splenectomy, and adhesive intestinal obstruction are being performed increasingly in neonates and children [3,25]. Rabbits have been reported as appropriate training models with which to practice the skills needed for laparoscopic surgery in neonates or infants due to their size and abdominal anatomy [11,19,20].…”

“…Rabbits have been reported as appropriate training models with which to practice the skills needed for laparoscopic surgery in neonates or infants due to their size and abdominal anatomy [11,19,20].…”