Hydrolysis and biomineralization of porous PLA microspheres and their influence on cell growth

Mineralization and drug release of hydroxyapatite/poly( l -lactic acid) nanocomposite scaffolds prepared by Pickering emulsion templating

“…And the obtained spectrum displayed the characteristic peaks associated with CO 3 2− groups at 875, 1385 and 1460 cm −1 , This indicated that the apatite deposited on the scaffolds were carbonated apatite, which was similar in composition and structure to the natural apatite in human bone. In fact, several research groups have reported that carbonated apatite particles have been obtained from the bioactive materials mineralized in SBF [12,38,40].…”

Porous Inorganic Drug Delivery Systems—a Review

“…These particles have been engineered/synthesised from a variety of synthetic polymers (i.e. poly(lactic-co-glycolic acid) (PLGA) (46,47), poly lactic acid (PLA) (48,49), poly(methyl methacrylate) (50), poly-(methyl ethyl cyanoacrylate)(51), polyacrylamide (52) and Eudragit (53)). In addition, several natural polymers (such as; chitosan (54), polysucrose (55) and alginate (56)) have also been used for porous particle synthesis.…”

Conversion of Biomass into Bioplastics and Their Potential Environmental Impacts

“…Bioplastics made from PLA shows the similar properties as those made from petroleum derived polyethylene terephthalate polymer. Besides applications in plastics, PLA derived bioplastics are also used extensively in biomedical applications, such as sutures, stents, dialysis devices, drug capsules, and evaluated as a matrix for tissue engineering (Park et al, 2008;Shi et al, 2010;Shi et al, 2009;Yao et al, 2009). Polyhydroxyalkanoates (PHAs) derived plastics are considered as the best candidates to replace the current petroleum-based plastics due to their durability in use and wide spectrum of properties.…”