Hydrolysis and photolysis of hexachlorocyclopentadiene

Threshold dosages of the photoisomers of cyclodiene insecticides, namely photochlordane, photodieldrin, and photoheptachlor, for the induction of hepatic microsomal cytochrome P450 (P450) and liver hypertrophy in male rats were at least one-quarter of those reported for corresponding parent cyclodienes. Maximum increase in total P450 concentration (30%) and demethylases activities (100%) was always respectively one-third or one-tenth of that reported for parent cyclodienes. The P450 isozymic form induced by photoheptachlor resembled that induced by pentobarbital (P4502B1) in its substrate specificity, spectral characteristics, and electrophoretic mobility. The induction of P450 was initially followed by hepatic hypertrophy. However, higher dosages of photoisomers caused wasting and lowered both the liver weight and the activity of aniline hydroxylase while those of mirex and endrin, which also caused wasting and lowered aniline hydroxylase activity, continued causing further hepatic hypertrophy.

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Number of Dishes as an Indicator of Nutrient Intake in China.

Nakatsuka

Zhang

Watanabe

et al. 2002

Tohoku J. Exp. Med.

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The objectives of this analysis are to investigate if counting the number of dishes consumed per day is a rapid procedure for estimating daily nutrient intake in China, and to explore if urban-rural differences exist in the daily number of dishes. A nutritional survey (including dish number counting) was conducted on 499 adult women in six urban and four rural communities in China. The number of dishes was an influential variable in estimating intake of protein, animal protein, fat, animal fat, and some vitamins (e.g., vitamin B2) and minerals (e.g., zinc), but not of energy and carbohydrate. Intake of some nutrients (e.g., protein) was sufficient when people consume more than 10 dishes per day. Thus, the number of dishes is a useful indicator of sufficient intake of animal protein and fat as well as some micro-nutrients. The application of the dish number counting method showed that there was a significant difference between urban (11.9 dishes per day) and rural populations (7.9 dishes).

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Hydrolysis and photolysis of hexachlorocyclopentadiene

Cited by 3 publications

References 8 publications

Induction of Hepatic Cytochrome P-450 by Phenobarbital in Semi-aquatic Frog (Rana pipiens)

Induction of Hepatic Cytochrome P-450 by Phenobarbital in Semi-aquatic Frog (Rana pipiens)

Effects of photoisomers of cyclodiene insecticides on liver and microsomal cytochrome P450 in rats

Number of Dishes as an Indicator of Nutrient Intake in China.

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