Hydrolysis of active esters by polymer‐supported oximes: Influence of macromolecular characters

Aiswaryakumari, K.; Sreekumar, K.

doi:10.1002/(sici)1097-4628(19981017)70:3<493::aid-app10>3.3.co;2-3

Cited by 1 publication

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“…Polymer-bound mixed carboxylic dithiocarbamic anhydrides have been developed as reagents for the selective acylation of amino groups (Haridasan et al 1987). Polystyreneand polyacrolein-bound oximino dithiocarbonic anhydrides were also developed as reagents for the selective acylation of amino groups (Aiswaryakumari et al 1995;Aiswaryakumari and Sreekumar 1996).…”

Section: * For Correspondence 49mentioning

confidence: 99%

Polystyrene-supported hydroxamic dithiocarbonic anhydrides: A new class of acyl transfer reagents

Sophiamma

Sreekumar

1997

Proc. Indian Acad. Sci. (Chem. Sci.)

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Polystyrene-supported hydroxamic dithiocarbonicanhydrides were developed as a new class of regenerable solid phase reagents for acylating amino groups selectively. The reagent was prepared from crosslinked polystyrene support by a series of polymer analogous reactions. The crosslinking agents used were divinylbenzene (DVB) and ethyleneglycol dimethacrylate (EGDMA). The reagents were found to transfer their acyl groups to amines in solution at room temperature, yielding a solution of the corresponding amides. The influence of solvent, temperature, molar ratio and duration of reaction were studied to find out the optimum conditions. The spent reagent can be regenerated several times by a simple reaction, without significant loss in activity.

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Section: * For Correspondence 49mentioning

confidence: 99%